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51497 NELFCD

51497

NELFCD

negative elongation factor complex member C/D

protein-coding

Homo sapiens

基因描述

Type Description
Definition negative elongation factor complex member C/D

研究结论

Date Results Publications
2019-11-30 12:55:00 NELFCD polymorphisms are associated with jaundice-stage progression in primary biliary cholangitis. 29795304
2017-11-25 15:03:00 A positively charged face of NELF-AC is involved in RNA binding, whereas the opposite face of the NELF-AC subcomplex binds NELF-B. NELF-B is predicted to form a HEAT repeat fold, also binds RNA in vivo, and anchors the subunit NELF-E, which is confirmed to bind RNA in vivo. 27282391
2012-11-17 11:04:00 data show that NELF subunits exhibit highly specific subcellular localizations, such as in NELF bodies or in midbodies, and some shuttle actively between the nucleus and cytoplasm; loss of NELF from cells can lead to enlarged and/or multiple nuclei 19245807
2012-05-19 11:43:00 Trihydrophobin 1 phosphorylation by c-Src regulates MAPK/ERK signaling and cell migration. 22238675
2010-10-23 10:13:00 TH1 might play an important role in regulation of proliferation and invasion in human breast cancer. 20735431

名称对应

Type IDs
Synonymous HSPC130, NELF-C, NELF-D, TH1, TH1L
Gene
UniProtKB-ID: NELFD_HUMAN, H0UI80_HUMAN
UniprotKB: Q8IXH7, H0UI80
UniParc: UPI0000072780, UPI000006E952, UPI0000D4E339, UPI0000070632
EMBL: AJ238379, AK023310, AJ238375, CH471077, AJ238374, AK023927, AK293410, BC014952, AK001316, AL109840, AF161479
Ensembl: ENSG00000101158
KO: hsa:51497
Nucleutide sequences
EMBL-CDS: AAF29094.1, CAB64339.1, BAB14729.1, BAB14519.1, CAB64337.1, BAA91618.1, BAG56917.1, CAB64373.1, AAH14952.1, EAW75452.1, EAW75454.1, EAW75453.1
Gene_ORFName: HSPC130, hCG_28547
Ensembl_TRS: ENST00000652272, ENST00000602795
Protein sequencees
Ensembl_PRO: ENSP00000499018, ENSP00000473290
RefSeq: NP_945327.3
Others
UniRef100: UniRef100_Q8IXH7
UniRef90: UniRef90_Q8IXH7
UniRef50: UniRef50_Q8IXH7
UniGene: Hs.517148
CCDS: CCDS13473.2

全选

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