| Type | Description |
|---|---|
| Definition | hydroxysteroid 17-beta dehydrogenase 7 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-18 11:36:00 | Inhibition of 17beta-HSD7can provide a new basis for the design of combined endocrine therapy for breast cancer by controlling E2 and DHT, while up-regulating AR expression and stably controlling expression of ERalpha. | 31207361 |
| 2019-05-25 11:10:00 | Substrate affinity of 17beta-hydroxysteroid dehydrogenase type 7 toward estrone and 5alpha-dihydrotestosterone are similar. | 30227243 |
| 2017-08-26 12:48:00 | Inhibition of 17beta-HSD 7 modulates breast cancer protein profile and enhances apoptosis by down-regulating GRP78. | 28645527 |
| 2017-08-26 11:02:00 | Substrate inhibition of 17beta-HSD1 in tumor epithelial cells and regulation of 17beta-HSD7 by 17beta-HSD1 knockdown has been demonstrated. | 28554725 |
| 2016-08-13 10:42:00 | the dual functional 17beta-HSD7 is proposed as a novel target for estrogen-dependent breast cancer by regulating the balance of estradiol and dihydrotestosterone. | 25966904 |
| Type | IDs |
|---|---|
| Synonymous | PRAP, SDR37C1 |
| Gene |
UniProtKB-ID:
DHB7_HUMAN,
Q9H9C0_HUMAN,
A0A024R913_HUMAN
UniprotKB:
P56937,
Q9H9C0,
A0A024R913
UniParc:
UPI000002A7E3,
UPI00004C2D25,
UPI0000070811,
UPI000004C64C
EMBL:
BC007068,
AJ249179,
AF162759,
AJ250557,
AL445197,
CH471067,
AJ250553,
AF145023,
AY358962,
AK290741,
AF162762,
AF162767,
AF162765,
AJ250552,
AF098786,
AF162764,
BC065246,
AF162766,
AJ250554,
AJ250550,
BT007075,
AK022929,
AJ250556,
AJ250551,
AF162761,
AJ250555,
AF162763,
AL392003,
AJ250558,
AF162760
Ensembl:
ENSG00000132196
KO:
hsa:51478
|
| Nucleutide sequences |
EMBL-CDS:
AAP97275.1,
AAQ89321.1,
CAC20418.1,
EAW90716.1,
AAF09266.2,
AAH07068.1,
AAP35738.1,
AAF14537.1,
BAF83430.1,
AAH65246.1,
CAC88111.1,
BAB14312.1,
EAW90725.1,
EAW90720.1
Gene_ORFName:
UNQ2563/PRO6243,
hCG_2024989,
hCG_2024989
Ensembl_TRS:
ENST00000254521
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000254521
RefSeq:
NP_001291441.1,
NP_001291442.1,
NP_057455.1
|
| Others |
UniRef100:
UniRef100_P56937,
UniRef100_Q9H9C0
UniRef90:
UniRef90_P56937,
UniRef90_Q9H9C0
UniRef50:
UniRef50_G1T1C4,
UniRef50_P56937
UniGene:
Hs.492925
CCDS:
CCDS1242.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员