| Type | Description |
|---|---|
| Definition | LIM domain and actin binding 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:31:00 | LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation. | 32496561 |
| 2020-09-19 16:26:00 | EPLIN-alpha and -beta Isoforms Modulate Endothelial Cell Dynamics through a Spatiotemporally Differentiated Interaction with Actin. | 31644899 |
| 2019-03-09 11:19:00 | Study proposes a role for EPLIN's ability to regulate the aggressive characteristics of prostate cancer cells partially through regulating FAK/Src signaling. | 30098000 |
| 2018-09-01 10:39:00 | this study identifies LIMA1 as a key protein regulating intestinal cholesterol absorption. | 29880681 |
| 2018-05-05 11:40:00 | Reduction in the levels of hCDC14A and eplin mRNA is frequently associated with colorectal carcinoma and is correlated with poor prognosis. Authors therefore propose that eplin dephosphorylation by hCDC14A reduces actin dynamics to restrict tumor malignancy. | 28465438 |
| Type | IDs |
|---|---|
| Synonymous | EPLIN, LDLCQ8, SREBP3 |
| Gene |
UniProtKB-ID:
LIMA1_HUMAN
UniprotKB:
Q9UHB6
UniParc:
UPI0000EE6469,
UPI0000169A62,
UPI000002A907,
UPI000002A906,
UPI0000037BF2
EMBL:
BC136763,
BC110815,
AF198454,
AB209512,
AK000057,
BC001247,
AK023649,
AF218025,
AF157325,
CH471111,
AK000372,
AF198455,
AK000335,
BC010664,
AL136911,
AK314447
Ensembl:
ENSG00000050405
KO:
hsa:51474
|
| Nucleutide sequences |
EMBL-CDS:
CAB66845.1,
BAA91120.1,
AAG17267.1,
BAD92749.1,
EAW58135.1,
BAA91092.1,
AAF23756.1,
AAI10816.1,
AAH01247.2,
AAF67491.1,
BAA90914.1,
AAI36764.1,
BAG37056.1,
AAF23755.1,
BAB14625.1,
AAH10664.1
Gene_ORFName:
PP624
Ensembl_TRS:
ENST00000552823,
ENST00000552783,
ENST00000547825,
ENST00000394943,
ENST00000341247
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000340184,
ENSP00000448706,
ENSP00000450266,
ENSP00000448779,
ENSP00000378400
RefSeq:
NP_057441.1,
XP_016874918.1,
XP_011536757.1,
XP_016874919.1,
NP_001107018.1,
NP_001107019.1,
NP_001230704.1
|
| Others |
UniRef100:
UniRef100_Q9UHB6
UniRef90:
UniRef90_Q9UHB6
UniRef50:
UniRef50_Q9UHB6
UniGene:
Hs.525419
CCDS:
CCDS58230.1,
CCDS55826.1,
CCDS44877.1,
CCDS8802.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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