Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint.

Genetics     Melanie L Bailey , Tejomayee Singh , Patricia Mero , Jason Moffat , Philip Hieter

The endoplasmic reticulum-based acetyltransferases, ATase1 and ATase2, associate with the oligosaccharyltransferase to acetylate correctly folded polypeptides.

J Biol Chem     Yun Ding , Cosma D Dellisanti , Mi Hee Ko , Cynthia Czajkowski , Luigi Puglielli

Post-translational regulation of CD133 by ATase1/ATase2-mediated lysine acetylation.

J. Mol. Biol.     Anthony B Mak , Mariana Pehar , Allison M L Nixon , Rashida A Williams , Andrea C Uetrecht , Luigi Puglielli , Jason Moffat

Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces β-secretase (BACE1) levels and Aβ generation.

J Biol Chem     Yun Ding , Mi Hee Ko , Mariana Pehar , Frank Kotch , Noel R Peters , Yun Luo , Shahriar M Salamat , Luigi Puglielli

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

Genetic loci influencing kidney function and chronic kidney disease.

Nat Genet     John C Chambers , Weihua Zhang , Graham M Lord , Pim van der Harst , Debbie A Lawlor , Joban S Sehmi , Daniel P Gale , Mark N Wass , Kourosh R Ahmadi , Stephan J L Bakker , Jacqui Beckmann , Henk J G Bilo , Murielle Bochud , Morris J Brown , Mark J Caulfield , John M C Connell , H Terence Cook , Ioana Cotlarciuc , George Davey Smith , Ranil de Silva , Guohong Deng , Olivier Devuyst , Lambert D Dikkeschei , Nada Dimkovic , Mark Dockrell , Anna Dominiczak , Shah Ebrahim , Thomas Eggermann , Martin Farrall , Luigi Ferrucci , Jurgen Floege , Nita G Forouhi , Ron T Gansevoort , Xijin Han , Bo Hedblad , Jaap J Homan van der Heide , Bouke G Hepkema , Maria Hernandez-Fuentes , Elina Hypponen , Toby Johnson , Paul E de Jong , Nanne Kleefstra , Vasiliki Lagou , Marta Lapsley , Yun Li , Ruth J F Loos , Jian'an Luan , Karin Luttropp , Céline Maréchal , Olle Melander , Patricia B Munroe , Louise Nordfors , Afshin Parsa , Leena Peltonen , Brenda W Penninx , Esperanza Perucha , Anneli Pouta , Inga Prokopenko , Paul J Roderick , Aimo Ruokonen , Nilesh J Samani , Serena Sanna , Martin Schalling , David Schlessinger , Georg Schlieper , Marc A J Seelen , Alan R Shuldiner , Marketa Sjögren , Johannes H Smit , Harold Snieder , Nicole Soranzo , Timothy D Spector , Peter Stenvinkel , Michael J E Sternberg , Ramasamyiyer Swaminathan , Toshiko Tanaka , Lielith J Ubink-Veltmaat , Manuela Uda , Peter Vollenweider , Chris Wallace , Dawn Waterworth , Klaus Zerres , Gerard Waeber , Nicholas J Wareham , Patrick H Maxwell , Mark I McCarthy , Marjo-Riitta Jarvelin , Vincent Mooser , Goncalo R Abecasis , Liz Lightstone , James Scott , Gerjan Navis , Paul Elliott , Jaspal S Kooner

New loci associated with kidney function and chronic kidney disease.

Nat Genet     Anna Köttgen , Cristian Pattaro , Carsten A Böger , Christian Fuchsberger , Matthias Olden , Nicole L Glazer , Afshin Parsa , Xiaoyi Gao , Qiong Yang , Albert V Smith , Jeffrey R O'Connell , Man Li , Helena Schmidt , Toshiko Tanaka , Aaron Isaacs , Shamika Ketkar , Shih-Jen Hwang , Andrew D Johnson , Abbas Dehghan , Alexander Teumer , Guillaume Paré , Elizabeth J Atkinson , Tanja Zeller , Kurt Lohman , Marilyn C Cornelis , Nicole M Probst-Hensch , Florian Kronenberg , Anke Tönjes , Caroline Hayward , Thor Aspelund , Gudny Eiriksdottir , Lenore J Launer , Tamara B Harris , Evadnie Rampersaud , Braxton D Mitchell , Dan E Arking , Eric Boerwinkle , Maksim Struchalin , Margherita Cavalieri , Andrew Singleton , Francesco Giallauria , Jeffrey Metter , Ian H de Boer , Talin Haritunians , Thomas Lumley , David Siscovick , Bruce M Psaty , M Carola Zillikens , Ben A Oostra , Mary Feitosa , Michael Province , Mariza de Andrade , Stephen T Turner , Arne Schillert , Andreas Ziegler , Philipp S Wild , Renate B Schnabel , Sandra Wilde , Thomas F Munzel , Tennille S Leak , Thomas Illig , Norman Klopp , Christa Meisinger , H-Erich Wichmann , Wolfgang Koenig , Lina Zgaga , Tatijana Zemunik , Ivana Kolcic , Cosetta Minelli , Frank B Hu , Asa Johansson , Wilmar Igl , Ghazal Zaboli , Sarah H Wild , Alan F Wright , Harry Campbell , David Ellinghaus , Stefan Schreiber , Yurii S Aulchenko , Janine F Felix , Fernando Rivadeneira , Andre G Uitterlinden , Albert Hofman , Medea Imboden , Dorothea Nitsch , Anita Brandstätter , Barbara Kollerits , Lyudmyla Kedenko , Reedik Mägi , Michael Stumvoll , Peter Kovacs , Mladen Boban , Susan Campbell , Karlhans Endlich , Henry Völzke , Heyo K Kroemer , Matthias Nauck , Uwe Völker , Ozren Polasek , Veronique Vitart , Sunita Badola , Alexander N Parker , Paul M Ridker , Sharon L R Kardia , Stefan Blankenberg , Yongmei Liu , Gary C Curhan , Andre Franke , Thierry Rochat , Bernhard Paulweber , Inga Prokopenko , Wei Wang , Vilmundur Gudnason , Alan R Shuldiner , Josef Coresh , Reinhold Schmidt , Luigi Ferrucci , Michael G Shlipak , Cornelia M van Duijn , Ingrid Borecki , Bernhard K Krämer , Igor Rudan , Ulf Gyllensten , James F Wilson , Jacqueline C Witteman , Peter P Pramstaller , Rainer Rettig , Nick Hastie , Daniel I Chasman , W H Kao , Iris M Heid , Caroline S Fox

Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels.

J Biol Chem     Mi Hee Ko , Luigi Puglielli

Human-specific nonsense mutations identified by genome sequence comparisons.

Hum. Genet.     Yoonsoo Hahn , Byungkook Lee

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

Proc. Natl. Acad. Sci. U.S.A.     Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team