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51458 RHCG

51458

RHCG

Rh family C glycoprotein

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rh family C glycoprotein

研究结论

Date Results Publications
2020-07-18 12:31:00 High RhCG level was correlated with poor prognosis of gastric cancer patients. 31756312
2020-07-18 10:53:00 Our study reveals that RHCG acts as a tumor suppressor gene that plays a crucial role in inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma. 31170090
2018-12-22 12:31:00 RhCG and H+ATPases are located within the same cellular protein complex in the kidney and this interaction is required for maximal urinary acidification by H+-ATPases, a prerequisite for efficient NH3 secretion and urine excretion of NH4+. 29054531
2018-12-01 10:09:00 RHCG was down-regulated in cervical cancers compared to that in normal cervical tissues, and further decreased in cervical cancer cell lines. Functionally, RHCG overexpression reduced cervical cancer cell proliferation and migration, as evidenced by the decreased transforming growth factor (TGF)-beta1, matrix metalloproteinase (MMP)-2 and MMP-9 expressions in cancer cells. 29852177
2018-11-24 11:04:00 The results support the notion that RHCG is a novel tumor suppressor gene that plays an important role in the development and progression of ESCC. 29290801

名称对应

Type IDs
Synonymous C15orf6, PDRC2, RHGK, SLC42A3
Gene
UniProtKB-ID: RHCG_HUMAN
UniprotKB: Q9UBD6
UniParc: UPI00000343FD
EMBL: AF219981, AF219985, AC013391, AF193809, AK290899, BC030965, AY257182, AF219983, AF219982, AF081497, CH471101, AF284446, AF219984, AF219986, AK313238
Ensembl: ENSG00000140519
KO: hsa:51458
Nucleutide sequences
EMBL-CDS: BAF83588.1, AAD55748.1, AAG02414.1, EAX02051.1, AAG02171.1, AAP81044.1, BAG36049.1, AAF19372.1, AAH30965.1
Ensembl_TRS: ENST00000268122
Protein sequencees
Ensembl_PRO: ENSP00000268122
RefSeq: NP_001307970.1, NP_057405.1
Others
UniRef100: UniRef100_Q9UBD6
UniRef90: UniRef90_Q9UBD6
UniRef50: UniRef50_Q9UBD6
UniGene: Hs.459284
CCDS: CCDS10351.1

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