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51455 REV1

51455

REV1

REV1 DNA directed polymerase

protein-coding

Homo sapiens

基因描述

Type Description
Definition REV1 DNA directed polymerase

研究结论

Date Results Publications
2021-03-13 13:25:00 Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs. 33555350
2020-11-21 13:27:00 Exome Sequencing in Individuals with Isolated Biliary Atresia. 32066793
2020-06-06 13:19:00 elevated expression of Rev1 alone is sufficient to confer enhanced UV-damage tolerance and that this tolerance depends on its physical interaction with monoubiquitinated PCNA and Polzeta but is independent of Poleta. 30963698
2019-06-22 11:21:00 Study reports the solution NMR structure of a 108-residue fragment of human REV1 encompassing the two putative ubiquitin-binding motifs UBM1 and UBM2 in complex with ubiquitin. While in mammals UBM1 and UBM2 are both required for optimal association of REV1 with replication factories after DNA damage, only REV1 UBM2 binds ubiquitin. 29778604
2019-03-30 12:28:00 RAD51 regulates REV1 recruitment to DNA double-strand break sites via pulsed laser microirradiation. 30465533

名称对应

Type IDs
Synonymous AIBP80, REV1L
Gene
UniProtKB-ID: REV1_HUMAN, Q49AI5_HUMAN
UniprotKB: Q9UBZ9, Q49AI5
UniParc: UPI00000709C7, UPI00000729BE, UPI000056F180, UPI0000073A14
EMBL: AC018690, AF357886, AF206019, AB047646, AF151538, BC037734, AJ131720, AK002087
Ensembl: ENSG00000135945
KO: hsa:51455
Nucleutide sequences
EMBL-CDS: BAA92079.1, CAB38231.1, AAK43708.1, BAB21441.1, AAF06731.1, AAF18986.1, AAY24314.1, AAH37734.1
Ensembl_TRS: ENST00000258428, ENST00000393445
Protein sequencees
Ensembl_PRO: ENSP00000377091, ENSP00000258428
RefSeq: XP_016859802.1, NP_001308384.1, XP_016859801.1, NP_001308383.1, NP_001308387.1, XP_011509643.1, XP_016859804.1, XP_016859798.1, XP_024308728.1, NP_001032961.1, NP_057400.1, NP_001308388.1, XP_016859800.1, XP_016859803.1, NP_001308389.1, XP_016859799.1
Others
UniRef100: UniRef100_Q49AI5, UniRef100_Q9UBZ9
UniRef90: UniRef90_Q9UBZ9-2, UniRef90_Q9UBZ9
UniRef50: UniRef50_Q9UBZ9, UniRef50_Q9UBZ9-2
UniGene: Hs.443077
CCDS: CCDS2045.1, CCDS42722.1

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