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51454 GULP1

51454

GULP1

GULP PTB domain containing engulfment adaptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition GULP PTB domain containing engulfment adaptor 1

研究结论

Date Results Publications
2020-06-13 11:42:00 Results indicate that GULP, engulfment adaptor PTB domain containing 1 (GULP1) threonine 35 (T35) phosphorylation is a mechanism for the regulation of GULP1-amyloid beta precursor protein (APP) interaction and thereby APP processing. 31373844
2020-05-16 11:14:00 the phagocytic adaptor protein Gulp1 regulates EphB/ephrinB trogocytosis to achieve efficient cell rearrangements of cultured cells and during embryonic development 31409653
2020-04-25 10:58:00 The knockdown of GULP1 and ABR using siRNAs decreased phagocytosis by 40%. 31516309
2019-09-14 13:04:00 GULP1 methylation was associated with clinicopathological parameters such as stage III/IV, poorly differentiated grade, residual disease, worse overall and disease specific survival in ovarian cancer. 29964205
2017-12-23 12:56:00 This study highlights and provides new implications for the role of GULP1 associated molecular mechanism(s) in COPD-emphysema development or progression. 28284325

名称对应

Type IDs
Synonymous CED-6, CED6, GULP
Gene
UniProtKB-ID: GULP1_HUMAN
UniprotKB: Q9UBP9
UniParc: UPI000188199D, UPI00000722B9, UPI0000031CE3, UPI0000140380
EMBL: AC104131, AC092598, AC125490, AF191771, AC108493, CH471058, AK314498, AF200715, AC133606, AK298626, AK055718, BC001103
Ensembl: ENSG00000144366
KO: hsa:51454
Nucleutide sequences
EMBL-CDS: BAG60802.1, EAX10917.1, AAY24122.1, AAX93242.1, EAX10914.1, EAX10915.1, AAF18975.1, AAF08006.1, EAX10913.1, BAG37098.1, AAH01103.1
Ensembl_TRS: ENST00000409843, ENST00000410051, ENST00000409805, ENST00000409609, ENST00000409580, ENST00000409637, ENST00000409830, ENST00000359135
Protein sequencees
Ensembl_PRO: ENSP00000386867, ENSP00000387171, ENSP00000386402, ENSP00000386732, ENSP00000387144, ENSP00000387013, ENSP00000386289, ENSP00000352047
RefSeq: NP_001362865.1, NP_001362869.1, NP_001362875.1, XP_016859796.1, NP_001362877.1, NP_001362866.1, NP_001362860.1, NP_057399.1, NP_001362878.1, XP_011509634.1, XP_006712647.1, NP_001239598.1, NP_001362867.1, NP_001362871.1, XP_011509633.1, NP_001362854.1, XP_016859795.1, NP_001362864.1, NP_001362868.1, XP_006712646.1, XP_011509637.1, XP_011509635.1, NP_001362876.1, NP_001362863.1, NP_001239597.1, NP_001362857.1, NP_001362855.1, NP_001362881.1, NP_001362880.1, NP_001362856.1, NP_001362870.1, XP_011509631.1, NP_001362872.1, NP_001362858.1, NP_001362873.1, NP_001362879.1, NP_001362861.1, NP_001362882.1, NP_001362862.1, XP_006712652.1, XP_006712643.1, NP_001362859.1, XP_006712645.1, NP_001362874.1
Others
UniRef100: UniRef100_Q9UBP9
UniRef90: UniRef90_Q9UBP9
UniRef50: UniRef50_Q9UBP9
UniGene: Hs.470887, Hs.712910
CCDS: CCDS2295.1, CCDS58742.1, CCDS58743.1

全选

研究热度

研究结论
热点单位
排名 科研单位 文献
1

University of Toronto

2
2

Ulm University

2
3

Biogen Inc., 250 Binney Street, Cambridge, Massachusetts 02142, USA.

1
4

Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

1
5

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

1
热点人员
排名 研究人员 文献
1

In-San Kim

3
2

Joao A Paulo

2
3

John Szpyt

2
4

Steven P Gygi

2
5

Fana Gebreab

2
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