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51444 RNF138

51444

RNF138

ring finger protein 138

protein-coding

Homo sapiens

基因描述

Type Description
Definition ring finger protein 138

研究结论

Date Results Publications
2019-09-21 10:05:00 data suggest that RNF138 modulates the cisplatin resistance in the GC cells, thus serving as a potential drug target to challenge chemotherapy failure. In addition, RNF138 can also be used as a marker to monitor the development of cisplatin resistance in GC treatment. 30260263
2019-01-26 12:41:00 The role of RNF138 in glioblastoma and identify rpS3 as a crucial substrate of ubiquitination by RNF138, which underlies the radioresistance of glioblastoma. 29371697
2018-12-22 11:22:00 Study suggested that RNF138 was important for the proliferation, migration and invasion of glioma cells. Its downregulation inhibited the process of EMT by suppressing Erk signaling pathway in glioma. 30272353
2017-08-19 12:31:00 This study identify RNF138 as the E3 ubiquitin ligase promoting EA2-associated aberrant degradation of human CaV2.1 protein. 28167673
2017-07-15 12:00:00 Rad51d mediated by E3 Ligase Rnf138 has a role in the homologous recombination repair pathway 27195665

名称对应

Type IDs
Synonymous HSD-4, NARF, STRIN, hNARF
Gene
UniProtKB-ID: RN138_HUMAN, A0A140VJT9_HUMAN
UniprotKB: Q8WVD3, A0A140VJT9
UniParc: UPI00000702BA, UPI0000072125
EMBL: HM005478, AF162680, BT006878, AK315761, BC018107, AK023579, CR457150, CH471088, AL133557
Ensembl: ENSG00000134758
KO: hsa:51444
Nucleutide sequences
EMBL-CDS: AAD46623.2, CAB63712.1, BAB14614.1, AAP35524.1, EAX01280.1, BAG38114.1, CAG33431.1, AAH18107.1, AEE61076.1
Gene_ORFName: HSD4, HSD-4
Ensembl_TRS: ENST00000261593, ENST00000257190
Protein sequencees
Ensembl_PRO: ENSP00000257190, ENSP00000261593
RefSeq: XP_005258342.1, XP_005258343.1, NP_937761.1, NP_057355.2, NP_001178253.2
Others
UniRef100: UniRef100_Q8WVD3
UniRef90: UniRef90_Q8WVD3
UniRef50: UniRef50_Q8WVD3
UniGene: Hs.302408
CCDS: CCDS11903.1, CCDS11904.1

全选

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