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51433 ANAPC5

51433

ANAPC5

anaphase promoting complex subunit 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition anaphase promoting complex subunit 5

研究结论

Date Results Publications
2018-05-19 11:44:00 coexpression of APC5 and Axin genes significantly downregulated Wnt signaling in human SW480 CRC cells and inhibited cell growth. 28731177
2011-01-15 10:49:00 Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1. 20686030
2010-02-08 11:22:00 Studies indicate that APC/C(Cdh1) is required to maintain genomic stability. 19826416
2010-01-21 00:00:00 Results show that Apc5 binds the poly(A) binding protein (PABP), which directly binds the internal ribosome entry site (IRES) element of platelet-derived growth factor 2 mRNA. 15082755
2010-01-21 00:00:00 APC5 and APC7 suppress E1A-mediated transformation in a CBP/p300-dependent manner, indicating that these components of the APC/C may be targeted during cellular transformation 16319895

名称对应

Type IDs
Synonymous APC5
Gene
UniProtKB-ID: APC5_HUMAN, F5H0F9_HUMAN, B4DFK4_HUMAN
UniprotKB: Q9UJX4, F5H0F9, B4DFK4
UniParc: UPI0000D46497, UPI000153D2BA, UPI000006DF80, UPI00001A9CC4, UPI0000E23450
EMBL: BX537687, BC006301, AC069209, BC034243, AK294139, AC048337, BC001081, AK025614, BC001950, AF191339
Ensembl: ENSG00000089053
KO: hsa:51433
Nucleutide sequences
EMBL-CDS: AAF05753.1, AAH34243.1, AAH01081.1, AAH01950.1, CAD97812.1, AAH06301.1, BAG57465.1
Ensembl_TRS: ENST00000441917, ENST00000261819, ENST00000541887
Protein sequencees
Ensembl_PRO: ENSP00000261819, ENSP00000415061, ENSP00000439875
RefSeq: NP_001131031.1, XP_016874913.1, XP_016874912.1, NP_001317418.1, NP_057321.2
Others
UniRef100: UniRef100_Q49A41, UniRef100_F5H0F9, UniRef100_Q9UJX4
UniRef90: UniRef90_A1L1K3, UniRef90_Q9UJX4
UniRef50: UniRef50_Q9UJX4
UniGene: Hs.7101
CCDS: CCDS45000.1, CCDS9220.1

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