| Type | Description |
|---|---|
| Definition | angiomotin like 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:17:00 | AMOTL2 inhibits JUN Thr239 dephosphorylation by binding PPP2R2A to suppress the proliferation in non-small cell lung cancer cells. | 32950569 |
| 2020-06-13 11:55:00 | the localization of IQGAP1, AmotL2, and FKBP51 in malignant cells and tumor microenvironment of human GB tumors | 30794467 |
| 2017-09-30 12:45:00 | these results provide novel insights into a dual tumor suppressive function of AMOTL2 by targeting both YAP and AKT in liver size control and cancer prevention | 28368415 |
| 2016-10-22 12:17:00 | study reports for the first time that USP9X is a deubiquitinase of Angiomotin-like 2 (AMOTL2) and that AMOTL2 mono-ubiquitination is required for YAP inhibition | 26598551 |
| 2015-11-07 10:27:00 | mTORC2-mediated phosphorylation of AMOTL2 blocks its ability to inhibit YAP signaling. | 25998128 |
| Type | IDs |
|---|---|
| Synonymous | LCCP |
| Gene |
UniProtKB-ID:
AMOL2_HUMAN
UniprotKB:
Q9Y2J4
UniParc:
UPI000020A2BB,
UPI0001D3BD1B,
UPI0001D3BD1C,
UPI00001B216C
EMBL:
AK291616,
AB023206,
AC010207,
AK223598,
AK299270,
BC011454,
AF175966
Ensembl:
ENSG00000114019
KO:
hsa:51421
|
| Nucleutide sequences |
EMBL-CDS:
BAA76833.1,
AAD56361.2,
BAF84305.1,
BAD97318.1,
BAH12987.1,
AAH11454.1
Ensembl_TRS:
ENST00000513145,
ENST00000422605,
ENST00000514516,
ENST00000249883
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000409999,
ENSP00000249883,
ENSP00000424765,
ENSP00000425475
RefSeq:
NP_001265612.1,
NP_001265614.1,
XP_006713717.1,
NP_001350872.1,
XP_016862069.1,
XP_016862071.1,
NP_057285.3,
XP_016862070.1
|
| Others |
UniRef100:
UniRef100_Q9Y2J4
UniRef90:
UniRef90_Q9Y2J4
UniRef50:
UniRef50_Q9Y2J4
UniGene:
Hs.426312,
Hs.713601
CCDS:
CCDS33860.1,
CCDS87138.1,
CCDS63784.1,
CCDS63783.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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