| Type | Description |
|---|---|
| Definition | trafficking protein particle complex 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:27:00 | Deficiencies in vesicular transport mediated by TRAPPC4 are associated with severe syndromic intellectual disability. | 31794024 |
| 2019-11-02 12:49:00 | Findings identify a critical role of Synbindin in gut microbiome composition and Wnt signaling activation in colorectal carcinogenesis, and highlight Synbindin as an adaptor protein with multifaceted roles. | 30561033 |
| 2014-05-03 11:29:00 | Overexpression of TRAPPC4 increased colorectal carcinogenesis. | 23625650 |
| 2014-01-11 12:12:00 | Synbindin contributes to malignant phenotypes of GC by activating ERK on the Golgi, and synbindin is a potential biomarker and therapeutic target for GC. | 24104608 |
| 2011-12-17 10:38:00 | Data demonstrate that TRAPPC4 may regulate cell proliferation and apoptosis in CRC by interaction with ERK2 and phosphorylating ERK1/2 as well as modulating the subcellular location of pERK1/2 to activate the relevant signaling pathway. | 21826244 |
| Type | IDs |
|---|---|
| Synonymous | CGI-104, HSPC172, PTD009, SBDN, SYNBINDIN, TRS23 |
| Gene |
UniProtKB-ID:
TPPC4_HUMAN,
B4DF86_HUMAN,
E9PQE8_HUMAN,
J3KP27_HUMAN,
E9PKS9_HUMAN
UniprotKB:
Q9Y296,
B4DF86,
E9PQE8,
J3KP27,
E9PKS9
UniParc:
UPI00017A7669,
UPI0001F7873B,
UPI0001F7873A,
UPI0001F7873C,
UPI00017A6DCC,
UPI0000052E23
EMBL:
AK290520,
AF078862,
AK297422,
AF105025,
CH471065,
BC010866,
AF151862,
AP003392,
AF161520,
AK293977
Ensembl:
ENSG00000280495,
ENSG00000196655
KO:
hsa:51399
|
| Nucleutide sequences |
EMBL-CDS:
BAG59853.1,
EAW67430.1,
AAD44494.1,
AAH10866.1,
AAF29135.1,
BAF83209.1,
AAF21897.1,
AAD34099.1,
BAG57347.1
Gene_ORFName:
PTD009,
HSPC172,
CGI-104
Ensembl_TRS:
ENST00000629243,
ENST00000629713,
ENST00000533632,
ENST00000434101,
ENST00000528230,
ENST00000627703,
ENST00000359005,
ENST00000625526,
ENST00000630169,
ENST00000525303
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000405033,
ENSP00000436005,
ENSP00000487467,
ENSP00000486496,
ENSP00000486853,
ENSP00000436827,
ENSP00000351896,
ENSP00000485724,
ENSP00000486097,
ENSP00000435339
RefSeq:
NP_001305423.1,
NP_001305415.1,
NP_001305419.1,
NP_057230.1,
NP_001305421.1,
NP_001305417.1,
NP_001305418.1
|
| Others |
UniRef100:
UniRef100_Q9Y296,
UniRef100_E9PKS9,
UniRef100_E9PQE8,
UniRef100_J3KP27,
UniRef100_B4DF86
UniRef90:
UniRef90_Q9Y296,
UniRef90_J3KP27,
UniRef90_E9PQE8,
UniRef90_E9PKS9
UniRef50:
UniRef50_E9PKS9,
UniRef50_Q9Y296,
UniRef50_Q9VLI9
UniGene:
Hs.132760
CCDS:
CCDS81633.1,
CCDS8407.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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