| Type | Description |
|---|---|
| Definition | profilin 1 |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | nitric oxide and free radicals produced under different conditions could alter the functions of profilin through nitration, such as its interaction with actin and poly (l-proline). | 16428297 |
| 2010-01-21 00:00:00 | Profilin regulates actin dynamics both within the cytoplasm and inside the nuclei of developing mammalian embryos. | 16428331 |
| 2010-01-21 00:00:00 | Phosphorylation studies indicate that profilin dimers are not phosphorylated while teramers are preferentially phosphorylated over monomers. | 19523483 |
| 2010-01-21 00:00:00 | biophysical analysis reveals that the open nucleotide pocket of the profilin/actin x-ray structure is unstable and closes in the absence of profilin | 16428279 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PROF1_BOVIN
UniprotKB:
P02584
UniParc:
UPI00004CEC0D
EMBL:
BT021078,
BC102240
Ensembl:
ENSBTAG00000004915
KO:
bta:513895
|
| Nucleutide sequences |
EMBL-CDS:
AAI02241.1,
AAX09095.1
Ensembl_TRS:
ENSBTAT00000006465
|
| Protein sequencees |
Ensembl_PRO:
ENSBTAP00000006465
RefSeq:
NP_001015592.1
|
| Others |
UniRef100:
UniRef100_P02584
UniRef90:
UniRef90_P02584
UniRef50:
UniRef50_P62962
UniGene:
Bt.23180
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 19523483 |
Profilin oligomerization and its effect on poly (L-proline) binding and phosphorylation. Int. J. Biol. Macromol. Radhika V Korupolu , M S Achary , F Aneesa , K Sathish , R Wasia , M Sairam , H A Nagarajaram , Surya S Singh |
2009-10-01 |
PFN1
|
| 16428331 |
Hum. Reprod. Vanesa Y Rawe , Christopher Payne , Gerald Schatten |
2006-05-01 |
PFN1
|
| 16428279 |
Biophys. J. T J Minehardt , P A Kollman , R Cooke , E Pate |
2006-04-01 |
ACTB,
PFN1
|
| 16428297 |
Nitration of profilin effects its interaction with poly (L-proline) and actin. J. Biochem. S Kasina , Wasia Rizwani , K V N Radhika , Surya S Singh |
2005-12-01 |
PFN1
|
| 16305752 |
Characterization of 954 bovine full-CDS cDNA sequences. BMC Genomics Gregory P Harhay , Tad S Sonstegard , John W Keele , Michael P Heaton , Michael L Clawson , Warren M Snelling , Ralph T Wiedmann , Curt P Van Tassell , Timothy P L Smith |
2005-01-01 |
STK24,
UBAP2L,
ERCC2,
BTNL9,
ATRAID,
JMJD7,
LRWD1,
GPSM1,
RAD54L,
MKS1,
CCBL1,
FAM161B,
LOC107131293,
SERPINA1,
AK1,
AK2,
BGN,
CEL,
CLU,
DBH,
DCN,
DDC,
FOS,
NPC2,
LEP,
MOG,
OGN,
ST7,
TST,
ZP3,
ACTB,
PLIN2,
AOC3,
APOE,
ARNT,
CGN1,
COX4I1,
CTSV,
ECE1,
S1PR1,
FDX1,
FMOD,
FSHR,
FUT1,
GNB1,
GOT1,
HPRT1,
F11R,
LDHB,
M6PR,
MAOA,
MCM3,
MDH2,
MSRA,
NCF1,
NT5E,
OLR1,
P4HB,
SERPINE1,
PLAU,
PLOD1,
PON2,
PPIB,
PSAP,
SDHA,
SOD2,
SPP1,
TCN2,
TPI1,
VIL1,
WASL,
ACTG2,
ALDH1A1,
ANXA4,
ANXA5,
ANXA8L1,
BCAT2,
BLCAP,
C4BPA,
CCNB2,
CCNG1,
ACKR4,
DNAJC14,
COPZ1,
CPSF3,
CREB1,
CREB3,
CTBP2,
ECHS1,
EDNRA,
FABP3,
FABP5,
HADHB,
HSPA2,
HSPA8,
HYAL2,
IKBKB,
IKBKG,
IMPA1
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 12140684 |
Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Mamm. Genome Tad S Sonstegard , Anthony V Capuco , Joseph White , Curtis P Van Tassell , Erin E Connor , Jennifer Cho , Razvan Sultana , Larry Shade , James E Wray , Kevin D Wells , John Quackenbush |
2002-07-01 |
ATRAID,
LRWD1,
AOC2,
CCBL1,
CLU,
DCN,
NPC2,
OGN,
TST,
PLIN2,
APOE,
COX4I1,
CTSV,
FMOD,
GNB1,
LDHB,
M6PR,
MAOA,
MDH2,
MSRA,
P4HB,
PLAU,
PON2,
PPIB,
SDHA,
SOD2,
SPP1,
TPI1,
ACTG2,
ALDH1A1,
ANXA5,
BLCAP,
C4BPA,
CTBP2,
ECHS1,
FABP3,
FABP5,
HADHB,
HSPA2,
HSPA8,
KRT17,
PRDX1,
SPARC,
VDAC2,
ACADVL,
TAGLN2,
UQCRC2,
PRDX6,
BICD2,
SLC25A6,
BOLA-DMB,
BOLA-DRB3,
GABARAPL2,
BOLA-DQA2,
RPL3,
ANXA2,
HMGB1,
RPL10,
SUMO2,
RPLP0,
GOT2,
ATP6V1E1,
AKR1B1,
TPT1,
H3F3A,
ANXA1,
CASP4,
SQSTM1,
SERPINA5,
PRKCSH,
STC1,
COPE,
RTN3,
BANF1,
MRPL12,
HDAC1,
DGAT2,
RPS8,
DYNLL1,
RPL27A,
PDIA4,
HSPA5,
TKT,
PNP,
CAPZA2,
CXCR3,
NFE2L2,
TAPBP,
POLR2C,
ALDOC,
RALY,
TK1,
CD53,
PSMA3,
RALB,
MFNG,
SLC39A3,
UTP14A,
MAP3K12
|
| 10600384 |
J. Mol. Biol. I M Nodelman , G D Bowman , U Lindberg , C E Schutt |
1999-12-17 |
PFN2,
ACTB,
PFN1
|
| 8918942 |
The structure of an open state of beta-actin at 2.65 A resolution. J. Mol. Biol. J K Chik , U Lindberg , C E Schutt |
1996-11-08 |
ACTB,
PFN1
|
| 8046751 |
Crystallization and structure determination of bovine profilin at 2.0 A resolution. J. Mol. Biol. E S Cedergren-Zeppezauer , N C Goonesekere , M D Rozycki , J C Myslik , Z Dauter , U Lindberg , C E Schutt |
1994-07-29 |
PFN1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员