| Type | Description |
|---|---|
| Definition | phosphodiesterase 2A |
| Date | Results | Publications |
|---|---|---|
| 2017-12-16 11:04:00 | the well-known interaction between AIP and 2 different isoforms of phosphodiesterases (PDEs), PDE2A3 and PDE4A5, is of particular interest. While the interaction with over-expressed AIP does not seem to affect PDE2A3 function, the reported effect on PDE4A5 is, in contrast, reduced enzymatic activity. | 28427099 |
| 2016-05-21 11:43:00 | Lu AF33241 represents a novel PDE2A/PDE10A inhibitor tool which can penetrate the blood brain barrier. | 25941078 |
| 2016-04-23 10:48:00 | Epigenetic regulation of phosphodiesterases 2A and 3A underlies compromised beta-adrenergic Signaling in an induced pluripotent stem cell model of dilated cardiomyopathy. | 26095046 |
| 2015-12-19 12:07:00 | curcumin exerts its in vitro anti-angiogenic and in vivo anti-tumour properties through combined PDE2 and PDE4 inhibition | 25230992 |
| 2015-03-07 10:13:00 | PDE2A is involved in growth and invasion of human malignant melanoma PMP cells. | 24705027 |
| Type | IDs |
|---|---|
| Synonymous | CGS-PDE, PDE2A1, PED2A4, cGSPDE |
| Gene |
UniProtKB-ID:
PDE2A_HUMAN,
Q8IW54_HUMAN
UniprotKB:
O00408,
Q8IW54
UniParc:
UPI00004DCB01,
UPI000035E820,
UPI0000074557,
UPI000003B340,
UPI00003E2928,
UPI0000DFFDF4,
UPI0000D6A6EB
EMBL:
AK312434,
AK092278,
AY495087,
AY495088,
AY495089,
BC040974,
AK131525,
AP005019,
U67733,
AP003065
Ensembl:
ENSG00000186642
KO:
hsa:5138
|
| Nucleutide sequences |
EMBL-CDS:
AAS75514.1,
BAG52517.1,
BAG35343.1,
BAD18664.1,
AAS75515.1,
AAC51320.1,
AAS75513.1,
AAH40974.1
Ensembl_TRS:
ENST00000376450,
ENST00000444035,
ENST00000540345,
ENST00000334456,
ENST00000544570
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365633,
ENSP00000446399,
ENSP00000334910,
ENSP00000442256,
ENSP00000411657
RefSeq:
NP_001139681.1,
NP_001230713.1,
NP_002590.1,
NP_001137311.1,
XP_005274097.1
|
| Others |
UniRef100:
UniRef100_Q8IW54,
UniRef100_O00408
UniRef90:
UniRef90_O00408
UniRef50:
UniRef50_O00408
UniGene:
Hs.503163
CCDS:
CCDS53678.1,
CCDS8216.1,
CCDS73345.1,
CCDS44670.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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