| Type | Description |
|---|---|
| Definition | sorting nexin 7 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-20 10:54:00 | Overexpression of SNX7 in HEK293T cells reduces the levels of secreted Abeta and beta-cleaved N-terminal APP fragments (sAPPbeta). Moreover, SNX7 overexpression caused a significant reduction of the steady-state levels of APP as well as of the cell surface APP levels. | 29080748 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SNX7_HUMAN,
E9PNL2_HUMAN,
B4DP69_HUMAN
UniprotKB:
Q9UNH6,
E9PNL2,
B4DP69
UniParc:
UPI0000135B45,
UPI0001D62794,
UPI00017A77E3,
UPI0000205396,
UPI000002B3E7
EMBL:
BC010349,
CH471097,
AK223229,
AL627442,
AK298211,
AK293018,
BC018105,
AF121857,
BT006747,
CN483413,
AL049989
Ensembl:
ENSG00000162627
KO:
hsa:51375
|
| Nucleutide sequences |
EMBL-CDS:
CAB43229.1,
AAH18105.1,
AAH10349.1,
EAW72998.1,
BAF85707.1,
AAD27830.1,
EAW72996.1,
EAW72995.1,
BAD96949.1,
EAW72997.1,
AAP35393.1,
BAG60481.1
Ensembl_TRS:
ENST00000306121,
ENST00000529992
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000304429,
ENSP00000434731
RefSeq:
NP_689424.2,
XP_016856917.1,
NP_001351832.1,
NP_057060.2,
XP_011539866.1,
XP_006710740.1,
XP_016856914.1,
XP_016856915.1,
XP_016856916.1
|
| Others |
UniRef100:
UniRef100_E9PNL2,
UniRef100_Q9UNH6
UniRef90:
UniRef90_Q9UNH6,
UniRef90_Q9UNH6-2
UniRef50:
UniRef50_Q9UNH6,
UniRef50_Q9UNH6-2
UniGene:
Hs.197015
CCDS:
CCDS755.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 29080748 |
Overexpression of SNX7 reduces Aβ production by enhancing lysosomal degradation of APP. Biochem. Biophys. Res. Commun. Shaohua Xu , Lu Zhang , Lennart Brodin |
2018-01-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 23259602 |
Genome-wide association scan of dental caries in the permanent dentition. BMC Oral Health Xiaojing Wang , John R Shaffer , Zhen Zeng , Ferdouse Begum , Alexandre R Vieira , Jacqueline Noel , Ida Anjomshoaa , Karen T Cuenco , Myoung-Keun Lee , James Beck , Eric Boerwinkle , Marilyn C Cornelis , Frank B Hu , David R Crosslin , Cathy C Laurie , Sarah C Nelson , Kimberly F Doheny , Elizabeth W Pugh , Deborah E Polk , Robert J Weyant , Richard Crout , Daniel W McNeil , Daniel E Weeks , Eleanor Feingold , Mary L Marazita |
2012-12-21 | - |
| 23085988 |
Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules. EMBO J. Jan R T van Weering , Richard B Sessions , Colin J Traer , Daniel P Kloer , Vikram K Bhatia , Dimitrios Stamou , Sven R Carlsson , James H Hurley , Peter J Cullen |
2012-11-28 |
SNX33,
SNX8,
SNX30,
SNX7,
SNX9,
SNX1,
SNX4
|
| 21988832 |
Toward an understanding of the protein interaction network of the human liver. Mol. Syst. Biol. Jian Wang , Keke Huo , Lixin Ma , Liujun Tang , Dong Li , Xiaobi Huang , Yanzhi Yuan , Chunhua Li , Wei Wang , Wei Guan , Hui Chen , Chaozhi Jin , Juncheng Wei , Wanqiao Zhang , Yongsheng Yang , Qiongming Liu , Ying Zhou , Cuili Zhang , Zhihao Wu , Wangxiang Xu , Ying Zhang , Tao Liu , Donghui Yu , Yaping Zhang , Liang Chen , Dewu Zhu , Xing Zhong , Lixin Kang , Xiang Gan , Xiaolan Yu , Qi Ma , Jing Yan , Li Zhou , Zhongyang Liu , Yunping Zhu , Tao Zhou , Fuchu He , Xiaoming Yang |
2011-10-11 | - |
| 21873549 |
Diabetes Rona J Strawbridge , Josée Dupuis , Inga Prokopenko , Adam Barker , Emma Ahlqvist , Denis Rybin , John R Petrie , Mary E Travers , Nabila Bouatia-Naji , Antigone S Dimas , Alexandra Nica , Eleanor Wheeler , Han Chen , Benjamin F Voight , Jalal Taneera , Stavroula Kanoni , John F Peden , Fabiola Turrini , Stefan Gustafsson , Carina Zabena , Peter Almgren , David J P Barker , Daniel Barnes , Elaine M Dennison , Johan G Eriksson , Per Eriksson , Elodie Eury , Lasse Folkersen , Caroline S Fox , Timothy M Frayling , Anuj Goel , Harvest F Gu , Momoko Horikoshi , Bo Isomaa , Anne U Jackson , Karen A Jameson , Eero Kajantie , Julie Kerr-Conte , Teemu Kuulasmaa , Johanna Kuusisto , Ruth J F Loos , Jian'an Luan , Konstantinos Makrilakis , Alisa K Manning , MarÃa Teresa MartÃnez-Larrad , Narisu Narisu , Maria Nastase Mannila , John Ohrvik , Clive Osmond , Laura Pascoe , Felicity Payne , Avan A Sayer , Bengt Sennblad , Angela Silveira , Alena Stancáková , Kathy Stirrups , Amy J Swift , Ann-Christine Syvänen , Tiinamaija Tuomi , Ferdinand M van 't Hooft , Mark Walker , Michael N Weedon , Weijia Xie , Björn Zethelius , DIAGRAM Consortium , GIANT Consortium , MuTHER Consortium , CARDIoGRAM Consortium , C4D Consortium , Halit Ongen , Anders Mälarstig , Jemma C Hopewell , Danish Saleheen , John Chambers , Sarah Parish , John Danesh , Jaspal Kooner , Claes-Göran Ostenson , Lars Lind , Cyrus C Cooper , Manuel Serrano-RÃos , Ele Ferrannini , Tom J Forsen , Robert Clarke , Maria Grazia Franzosi , Udo Seedorf , Hugh Watkins , Philippe Froguel , Paul Johnson , Panos Deloukas , Francis S Collins , Markku Laakso , Emmanouil T Dermitzakis , Michael Boehnke , Mark I McCarthy , Nicholas J Wareham , Leif Groop , François Pattou , Anna L Gloyn , George V Dedoussis , Valeriya Lyssenko , James B Meigs , Inês Barroso , Richard M Watanabe , Erik Ingelsson , Claudia Langenberg , Anders Hamsten , Jose C Florez |
2011-10-01 | - |
| 21900206 |
A directed protein interaction network for investigating intracellular signal transduction. Sci Signal Arunachalam Vinayagam , Ulrich Stelzl , Raphaele Foulle , Stephanie Plassmann , Martina Zenkner , Jan Timm , Heike E Assmus , Miguel A Andrade-Navarro , Erich E Wanker |
2011-09-06 |
KCNE3,
HDAC6,
PDCD6IP,
ZNF605,
TOM1L1,
HMGXB4,
RANBP9,
RWDD2B,
SNUPN,
TSSC4,
ARPC3,
ACTR1B,
CDH13,
CEBPZ,
RBM5,
CDK4,
CDK5,
TRIM13,
EIF1,
DDX39A,
HNRNPR,
RABEPK,
SPRY2,
CDKN1A,
CDK2AP2,
LOC400927-CSNK1E,
RGS19,
CDKN2B,
DSCR3,
IKZF1,
NPM3,
TUBA1B,
TUBB3,
RACK1,
PIAS3,
NDC80,
YAP1,
CDIPT,
TUBGCP3,
TIMM17A,
TAB1,
FST,
STK25,
DEAF1,
KAT5,
GLRX3,
DCTN2,
PRDX4,
RABAC1,
DPYSL4,
CCT7,
CCT4,
DRAP1,
CENPB,
TXNIP,
NPRL2,
GNB5,
CERS1,
CFL1,
MGEA5,
PLK4,
RAI1,
GIPC1,
ZNF266,
UTP14A,
PGRMC1,
RAB10,
YIF1A,
JTB,
GADD45G,
AFG3L2,
C11orf58,
HNRNPA0,
PNRC1,
ADIRF,
COPS6,
IMMT,
SF3B2,
KIF2C,
RAB31,
ADAP1,
PIM2,
RCC1,
NUDT21,
SNRNP35,
CHD3,
STMN2,
HSF2BP,
SPACA9,
RPP14,
FGFR1OP,
FAF1,
ZWINT,
CHGA,
CDC37,
CHGB,
KAT7,
C14orf1,
NUDT5
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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