| Type | Description |
|---|---|
| Definition | ubiquitin protein ligase E3 component n-recognin 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:17:00 | UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target. | 32867711 |
| 2021-04-03 13:33:00 | The E3 ubiquitin ligase UBR5 interacts with TTC7A and may be associated with very early onset inflammatory bowel disease. | 33122718 |
| 2021-03-20 13:31:00 | UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD. | 32558906 |
| 2021-03-13 13:19:00 | UBR5 regulates proliferation and radiosensitivity in human laryngeal carcinoma via the p38/MAPK signaling pathway. | 32468011 |
| 2021-02-06 13:55:00 | UBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism. | 33340455 |
| Type | IDs |
|---|---|
| Synonymous | DD5, EDD, EDD1, HYD |
| Gene |
UniProtKB-ID:
UBR5_HUMAN
UniprotKB:
O95071
UniParc:
UPI000153C072,
UPI0000129BCB
EMBL:
AB020703,
AF006010,
AP002981,
BC137234,
AP002907,
U95000
Ensembl:
ENSG00000104517
KO:
hsa:51366
|
| Nucleutide sequences |
EMBL-CDS:
AAF88143.1,
AAD01259.2,
BAA74919.3,
AAI37235.1
Ensembl_TRS:
ENST00000220959,
ENST00000520539
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000429084,
ENSP00000220959
RefSeq:
XP_005251019.1,
XP_024302946.1,
NP_056986.2,
XP_011515406.2,
XP_024302947.1,
XP_016869023.1,
XP_016869022.1,
XP_011515407.2,
NP_001269802.1,
XP_011515408.2
|
| Others |
UniRef100:
UniRef100_O95071
UniRef90:
UniRef90_O95071
UniRef50:
UniRef50_O95071
UniGene:
Hs.492445
CCDS:
CCDS64946.1,
CCDS34933.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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