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51364 ZMYND10

51364

ZMYND10

zinc finger MYND-type containing 10

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger MYND-type containing 10

研究结论

Date Results Publications
2020-07-25 12:50:00 Study identified ZMYND10 as a tumor suppressor, which is downregulated in breast cancer due to its promoter hypermethylation, and suggested that ZMYND10 suppresses breast cancer metastasis by through the miR145-5p/NEDD9 signaling cascade. 31801619
2018-03-31 11:55:00 BLU suppressed tumor formation by strengthening the antitumor immunity. 28029652
2016-07-16 10:34:00 A novel frameshift mutation (c.367delC) in ZMYND10, unique for Slavic primary ciliary dyskinesia population (PCD), was found in homozygous state in two unrelated PCD patients. 26824761
2016-05-28 10:06:00 Data identified a novel functional BLU promoter that was regulated by Sp1. Furthermore, the hypermethylated -39 CpG in BLU proximal promoter directly reduced its binding with Sp1. 26043875
2015-11-28 10:45:00 Data show that the zinc finger MYND-type containing 10 protein BLU gene may be one of the key components of signaling networks controlling tumor microenvironment and angiogenesis. 25347745

名称对应

Type IDs
Synonymous BLU, CILD22, DNAAF7, FLU
Gene
UniProtKB-ID: ZMY10_HUMAN
UniprotKB: O75800
UniParc: UPI000002A4E8, UPI0000126A0E
EMBL: CH471055, AK096525, AK223343, BC033732, U70880, AC002481, AL833828, U70824
Ensembl: ENSG00000004838
KO: hsa:51364
Nucleutide sequences
EMBL-CDS: AAC24728.1, BAG53316.1, AAB67311.1, BAD97063.1, EAW65104.1, AAC24726.1, AAH33732.1, CAD38688.1
Gene_ORFName: LUCA12.4
Ensembl_TRS: ENST00000360165, ENST00000231749
Protein sequencees
Ensembl_PRO: ENSP00000353289, ENSP00000231749
RefSeq: NP_056980.2, XP_005265273.1, NP_001295308.1
Others
UniRef100: UniRef100_O75800
UniRef90: UniRef90_O75800
UniRef50: UniRef50_O75800
UniGene: Hs.526735, Hs.627171
CCDS: CCDS77747.1, CCDS2825.1

全选

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