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51348 KLRF1

51348

KLRF1

killer cell lectin like receptor F1

protein-coding

Homo sapiens

基因描述

Type Description
Definition killer cell lectin like receptor F1

研究结论

Date Results Publications
2017-12-02 12:26:00 NKp80 is a marker of natural killer (NK) cell maturity in secondary lymphoid tissues and supports NK cell development through a stage 4a intermediate with ILC3-associated features. 27373165
2017-07-15 10:06:00 In the second trimester, functional markers of Decidual natural killer activation, i.e., angiogenic factor production (e.g., vascular endothelial growth factor, interleukin-8, interferon-gamma), remained stable despite an increase in NKp80 or NKG2D surface expression. 26277900
2015-02-14 12:18:00 IL-15+IL-12 has an immunomodulatory effect on NK cell subsets from HIV-infected individuals viz down-regulation of iNKRs, elevation of activatory receptors NKp46 and NKG2D, and induction of coreceptor NKp80. 22715368
2013-11-23 10:35:00 our data report a previously unrecognized regulatory circuit enabling autonomous control of human NK cell responses via the NKp80-AICL axis. 23929856
2013-08-31 10:16:00 Two non-consensus amino acids of NKp80, in particular arginine 6, critically impair both hemi-immunoreceptor tyrosine-based activation motif phosphorylation and Syk recruitment. 23609447

名称对应

Type IDs
Synonymous CLEC5C, NKp80
Gene
UniProtKB-ID: KLRF1_HUMAN
UniprotKB: Q9NZS2
UniParc: UPI000006E220, UPI0000070D18, UPI0000071CE0, UPI000006F02A
EMBL: AJ305370, KF573680, AF267245, AC007068, AF175206, AF175207, CH471094, AF267244, BC098354
Ensembl: ENSG00000150045
KO: hsa:51348
Nucleutide sequences
EMBL-CDS: AAF37805.1, AAH98354.1, AAL14873.1, AAF37804.1, AAL14874.1, CAC29425.1, EAW96124.1
Ensembl_TRS: ENST00000617889, ENST00000279545, ENST00000354855, ENST00000612321
Protein sequencees
Ensembl_PRO: ENSP00000346919, ENSP00000483713, ENSP00000279545, ENSP00000483880
RefSeq: NP_001278752.1, NP_001278751.1, XP_016874904.1, NP_001353463.1, NP_057607.1
Others
UniRef100: UniRef100_Q9NZS2
UniRef90: UniRef90_Q9NZS2
UniRef50: UniRef50_Q9NZS2
UniGene: Hs.183125
CCDS: CCDS76527.1, CCDS76526.1, CCDS41750.1

全选

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