| Type | Description |
|---|---|
| Definition | programmed cell death 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 16:00:00 | PDCD2 functions as an evolutionarily conserved chaperone dedicated for the 40S ribosomal protein uS5 (RPS2). | 33245768 |
| 2019-05-25 12:04:00 | the present study elucidated for the first time, to the best of our knowledge, that PDCD2 sensitizes sorafenibresistant HepG2 cells to sorafenib by the downregulation of EMT. PDCD2 may serve as a potential therapeutic target in the treatment of sorafenibresistant liver cancer. | 30664177 |
| 2016-12-24 11:07:00 | PDCD2 and NCoR1 may act as tumor suppressors in Gastrointestinal stromal tumors cells through the Smad signaling pathway. | 26589942 |
| 2016-10-01 10:58:00 | PDCD2 may play an important role in tumor suppression in osteosarcoma. These mechanisms might be related to immune response induced by CD4(+) and CD8(+) T cells. | 26617804 |
| 2015-07-25 11:32:00 | Low PDCD2 expression is associated with gastric cancer. | 25111461 |
| Type | IDs |
|---|---|
| Synonymous | RP8, ZMYND7 |
| Gene |
UniProtKB-ID:
PDCD2_HUMAN,
A0A087WYJ3_HUMAN
UniprotKB:
Q16342,
A0A087WYJ3
UniParc:
UPI00004ED445,
UPI00004ED444,
UPI000013149C,
UPI00001612B2,
UPI0000D4D9F1,
UPI0001ED050E
EMBL:
S78085,
AK297343,
BC008378,
AY948416,
AL031259,
AY948417
Ensembl:
ENSG00000071994
KO:
hsa:5134
|
| Nucleutide sequences |
EMBL-CDS:
BAG59795.1,
AAB34865.1,
AAX51226.1,
AAX51225.1,
AAH08378.1
Ensembl_TRS:
ENST00000443345,
ENST00000541970,
ENST00000392090,
ENST00000537445,
ENST00000453163,
ENST00000614056
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000402524,
ENSP00000440572,
ENSP00000375940,
ENSP00000439467,
ENSP00000397272,
ENSP00000481860
RefSeq:
NP_659005.1,
NP_001186390.1,
NP_001186392.1,
NP_001186391.1,
NP_001186393.1,
NP_002589.2,
NP_001350584.1
|
| Others |
UniRef100:
UniRef100_A0A087WYJ3,
UniRef100_Q16342
UniRef90:
UniRef90_Q16342,
UniRef90_A0A2I3NDD8
UniRef50:
UniRef50_Q16342,
UniRef50_A0A2I3GRB2
UniGene:
Hs.367900
CCDS:
CCDS56461.1,
CCDS47521.1,
CCDS56462.1,
CCDS56460.1,
CCDS5316.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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