| Type | Description |
|---|---|
| Definition | dishevelled binding antagonist of beta catenin 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 11:28:00 | We identified DACT1 as a negative regulator in type I EOC, protecting against malignant expansion by inhibiting canonical Wnt signalling and cis-platinum resistance by regulating autophagy. | 28839145 |
| 2019-02-16 10:05:00 | This study demonstrates that cyclin G2 suppresses Wnt/beta-catenin signaling and inhibits gastric cancer cell growth and migration through Dapper1. | 30547803 |
| 2018-02-24 11:36:00 | DACT1alpha plays a pivotal role as a potential tumor suppressor in migration and invasion of gastric cancer. DACT1alpha methylation may serve as a biomarker for the prognosis of gastric cancer. | 27833078 |
| 2018-01-13 14:49:00 | Findings suggest that the DACT1 c.1256G>A nonsense variant is causative of a specific genetic syndrome with features overlapping Townes-Brocks syndrome. | 28054444 |
| 2017-11-25 14:08:00 | Dapper1 attenuates hepatic gluconeogenesis and lipogenesis in Ttype 2 diabetes. | 28237722 |
| Type | IDs |
|---|---|
| Synonymous | DAPPER, DAPPER1, DPR1, FRODO, HDPR1, TBS2, THYEX3 |
| Gene |
UniProtKB-ID:
DACT1_HUMAN
UniprotKB:
Q9NYF0
UniParc:
UPI000013E4D3,
UPI0000E59B48
EMBL:
AL133312,
BK000256,
BX161433,
AF251079
Ensembl:
ENSG00000165617
KO:
hsa:51339
|
| Nucleutide sequences |
EMBL-CDS:
AAF65569.1,
CAD61905.1,
DAA00310.1
Ensembl_TRS:
ENST00000335867,
ENST00000395153
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000337439,
ENSP00000378582
RefSeq:
NP_001072988.1,
NP_057735.2
|
| Others |
UniRef100:
UniRef100_Q9NYF0
UniRef90:
UniRef90_Q9NYF0
UniRef50:
UniRef50_Q9NYF0
UniGene:
Hs.48950,
Hs.714204
CCDS:
CCDS41961.1,
CCDS9736.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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