| Type | Description |
|---|---|
| Definition | membrane spanning 4-domains A4A |
| Date | Results | Publications |
|---|---|---|
| 2019-11-23 10:47:00 | MS4A4A is a tetraspan molecule selectively expressed in macrophages during differentiation and polarization, essential for dectin-1-dependent activation of natural killer cell-mediated resistance to metastasis. | 31263276 |
| 2018-04-28 12:09:00 | MS4A4A is expressed at the plasma membrane in monocytes but not in granulocytes or lymphocytes. | 28303902 |
| 2017-03-22 10:19:00 | MS4A4A expression is significantly upregulated in human masticatory mucosa during wound healing | 28005267 |
| 2016-04-09 11:37:00 | MS4A4 in human mast cells effects ligand-induced KIT endocytosis pathways and reduced receptor recycling to the cell surface, thus promoting KIT signaling in the endosomes while reducing that in the plasma membrane. | 25717186 |
| 2013-10-26 10:11:00 | Single nucleotide polymorphisms in APOE-epsilon4, CLU and MS4A4A influence both Alzheimer disease risk and cerebrospinal fluid Amyloid-beta1-42 levels. | 23573206 |
| Type | IDs |
|---|---|
| Synonymous | 4SPAN1, CD20-L1, CD20L1, HDCME31P, MS4A4, MS4A7 |
| Gene |
UniProtKB-ID:
M4A4A_HUMAN,
Q4JF27_HUMAN,
A0A384MDW1_HUMAN
UniprotKB:
Q96JQ5,
Q4JF27,
A0A384MDW1
UniParc:
UPI000007094F,
UPI0000055AE7,
UPI000019A002,
UPI000011C81A
EMBL:
CH471076,
AF068288,
AB013102,
AB022821,
GQ891540,
AF350500,
AF354928,
AK075081,
BC020648,
AF237912
Ensembl:
ENSG00000110079
KO:
hsa:51338
|
| Nucleutide sequences |
EMBL-CDS:
AAH20648.1,
AAL08486.1,
AAF65507.1,
AAL56220.1,
AAK37594.1,
BAB61018.1,
BAB18738.1,
BAC11389.1,
ADO22402.1,
EAW73875.1
Gene_ORFName:
HDCME31P,
hCG_40406
Ensembl_TRS:
ENST00000337908,
ENST00000532114
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000338648,
ENSP00000434506
RefSeq:
XP_016873398.1,
NP_001230195.1,
NP_683876.1,
NP_076926.2
|
| Others |
UniRef100:
UniRef100_Q4JF27,
UniRef100_Q96JQ5
UniRef90:
UniRef90_Q96JQ5
UniRef50:
UniRef50_Q96JQ5
UniGene:
Hs.325960
CCDS:
CCDS58135.1,
CCDS7982.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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