| Type | Description |
|---|---|
| Definition | arginine and serine rich coiled-coil 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 12:54:00 | Our findings support the pathogenic role of biallelic loss-of-function RSRC1 variants in autosomal recessive intellectual disability, in addition to contributing to the phenotypic delineation of this emerging condition | 32227164 |
| 2020-01-04 10:43:00 | RSRC1 knockdown promoted the proliferation and migration of gastric cancer cells. In addition, the knockdown of RSRC1 decreased the expression of phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a potent tumor suppressor gene controlling cellular growth and viability. | 31257492 |
| 2019-06-29 10:04:00 | This study demonstrated that RSRC1 mutation affects intellect and behaviour through aberrant splicing and transcription, downregulating IGFBP3. | 29522154 |
| 2018-06-09 11:55:00 | RSRC1 rs6441201A allele was associated with increased neuroblastoma risk in Chinese children. | 29653227 |
| 2015-08-08 10:23:00 | Data indicate that arginine/serine-rich coiled-coil 1 (RSRC1) represses estrogen receptor beta (ERbeta) transcriptional activity via ERbeta SUMOylation. | 25937118 |
| Type | IDs |
|---|---|
| Synonymous | BM-011, SFRS21, SRrp53 |
| Gene |
UniProtKB-ID:
RSRC1_HUMAN
UniprotKB:
Q96IZ7
UniParc:
UPI000006EB23,
UPI000007311A
EMBL:
AF208853,
BC010357,
BC006982,
AK290334
Ensembl:
ENSG00000174891
KO:
hsa:51319
|
| Nucleutide sequences |
EMBL-CDS:
AAH10357.1,
AAF64267.1,
BAF83023.1,
AAH06982.1
Gene_ORFName:
BM-011
Ensembl_TRS:
ENST00000611884,
ENST00000295930,
ENST00000312179,
ENST00000464171,
ENST00000480820
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000481697,
ENSP00000419794,
ENSP00000295930,
ENSP00000308671,
ENSP00000420150
RefSeq:
XP_024309331.1,
NP_001258763.1,
NP_057709.2,
NP_001258767.1,
XP_024309328.1,
XP_024309330.1
|
| Others |
UniRef100:
UniRef100_Q96IZ7
UniRef90:
UniRef90_Q96IZ7
UniRef50:
UniRef50_Q96IZ7
UniGene:
Hs.591283
CCDS:
CCDS63822.1,
CCDS3181.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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