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51304 ZDHHC3

51304

ZDHHC3

zinc finger DHHC-type containing 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger DHHC-type containing 3

研究结论

Date Results Publications
2021-04-03 13:33:00 Antioxidant functions of DHHC3 suppress anti-cancer drug activities. 32986127
2018-01-06 11:01:00 DHHC3-mediated protein palmitoylation supports breast tumor growth by modulating cellular oxidative stress and senescence. 29055014
2017-09-30 11:31:00 HSV-1 UL20 binds to GODZ (also known as DHHC3), a Golgi apparatus-specific Asp-His-His-Cys (DHHC) zinc finger protein. a GODZ dominant-negative mutant and an inhibitor of palmitoylation reduced HSV-1 titers and altered the localization of UL20 and glycoprotein K. UL20 is palmitoylated by GODZ, and this UL20 palmitoylation is required for HSV-1 infectivity. 28724772
2013-09-14 10:36:00 In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes. 23687301
2012-10-20 10:20:00 GODZ regulates plasma membrane targeting of DR4 and thus TRAIL/DR4-mediated apoptosis in cancer cells. 22240897

名称对应

Type IDs
Synonymous DHHC-3, DHHC3, GODZ, ZNF373
Gene
UniProtKB-ID: ZDHC3_HUMAN, F8W6M3_HUMAN
UniprotKB: Q9NYG2, F8W6M3
UniParc: UPI000002B749, UPI000198CACA, UPI000013C380
EMBL: AC098649, AF247703, AY605661, AC104165, BC015467, AF441791
Ensembl: ENSG00000163812
KO: hsa:51304
Nucleutide sequences
EMBL-CDS: AAV83779.1, AAF63570.1, AAL34547.1, AAH15467.1
Gene_ORFName: HSD49
Ensembl_TRS: ENST00000296127, ENST00000424952, ENST00000342790
Protein sequencees
Ensembl_PRO: ENSP00000395502, ENSP00000296127, ENSP00000345268
RefSeq: XP_024309323.1, XP_016862057.1, XP_024309326.1, XP_016862059.1, NP_001336305.1, XP_024309324.1, XP_024309327.1, NP_001336307.1, NP_001336309.1, NP_001336310.1, NP_001336306.1, NP_001336308.1, XP_016862051.1, NP_001317690.1, XP_016862050.1, XP_024309325.1, NP_057682.1, XP_016862054.1, NP_001128651.1
Others
UniRef100: UniRef100_Q9NYG2, UniRef100_F8W6M3
UniRef90: UniRef90_Q9NYG2
UniRef50: UniRef50_Q9NYG2
UniGene: Hs.61430
CCDS: CCDS46811.1, CCDS2724.1

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