| Type | Description |
|---|---|
| Definition | guanosine monophosphate reductase 2 |
| Date | Results | Publications |
|---|---|---|
| 2013-06-01 11:48:00 | Loss of expression of GMPR2 and PPARalpha is associated with breast cancer basal phenotype; indicating that they may play a role in carcinogenesis. | 23208589 |
| 2012-02-04 11:33:00 | A single crystal structure of human GMPR type 2 with IMP and NADPH fortuitously captures three different states, each of which mimics a distinct step in the catalytic cycle of guanosine monophosphate reductase(GMPR). | 22037469 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | 21048031 |
| 2010-01-21 00:00:00 | Data suggest the existence of two distinct types of human GMP reductase molecular species, which can be used to explain the bimodal saturation curve noted with purified human erythrocyte GMP reductase. | 12009299 |
| 2010-01-21 00:00:00 | GMPR2 is a novel human GMP reductase, and overexpression of GMPR2 can promote the monocytic differentiation of HL-60 leukemia cells. | 12669231 |
| Type | IDs |
|---|---|
| Synonymous | GMPR 2 |
| Gene |
UniProtKB-ID:
GMPR2_HUMAN,
H0YNJ6_HUMAN,
Q6PKC0_HUMAN
UniprotKB:
Q9P2T1,
H0YNJ6,
Q6PKC0
UniParc:
UPI0000350798,
UPI000000CC1C,
UPI0000D4BCF6,
UPI0000374739,
UPI000000CBD0
EMBL:
BC009832,
AL096870,
BC093039,
AF135159,
BX247993,
BC003053,
CH471078,
BC008021,
AB032903,
CR457156,
BX161436,
AF419346
Ensembl:
ENSG00000284752,
ENSG00000100938
KO:
hsa:51292
|
| Nucleutide sequences |
EMBL-CDS:
CAD62327.1,
AAG09132.1,
EAW66051.1,
CAG33437.1,
EAW66057.1,
BAA93080.1,
AAH93039.1,
EAW66053.1,
EAW66056.1,
CAD61908.1,
AAN32701.1,
AAH09832.1,
EAW66054.1,
AAH08021.2,
EAW66055.1,
AAH03053.1
Gene_ORFName:
hCG_40198
Ensembl_TRS:
ENST00000399440,
ENST00000355299,
ENST00000645781,
ENST00000642276,
ENST00000420554,
ENST00000647320,
ENST00000644066,
ENST00000456667,
ENST00000643803,
ENST00000559836,
ENST00000557854
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000496234,
ENSP00000347449,
ENSP00000453299,
ENSP00000496504,
ENSP00000495708,
ENSP00000495583,
ENSP00000382369,
ENSP00000494224,
ENSP00000405743,
ENSP00000392859,
ENSP00000454038
RefSeq:
NP_001337953.1,
NP_001002001.1,
NP_001002000.1,
NP_001337952.1,
NP_001337951.1,
NP_001269952.1,
NP_057660.2,
NP_001269950.1,
NP_001002002.1,
NP_001337954.1,
NP_001337955.1,
NP_001269951.1
|
| Others |
UniRef100:
UniRef100_H0YNJ6,
UniRef100_Q9P2T1
UniRef90:
UniRef90_H0YNJ6,
UniRef90_Q9P2T1
UniRef50:
UniRef50_Q9P2T1
UniGene:
Hs.368855
CCDS:
CCDS61419.1,
CCDS41935.1,
CCDS45087.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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