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51289 RXFP3

51289

RXFP3

relaxin family peptide receptor 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition relaxin family peptide receptor 3

研究结论

Date Results Publications
2019-11-30 12:03:00 present work shed new light on the interaction mechanism of RXFP3 and RXFP4 with agonists and antagonists, and also provided a novel approach for interaction studies of some plasma membrane receptors with their ligands. 30684458
2018-09-22 11:09:00 This study indicated that RXFP3 mainly localised in the post-acrosomal region of sperm head and neck. 29159832
2018-05-19 11:49:00 The role of these four INSL5 determinants in distinguishing RXFP4 from RXFP3. 27404393
2018-01-27 11:32:00 Therefore, we conclude that stapling of the relaxin3 B chain does not compromise its ability to activate RXFP3 and is a promising method for developing stable peptide agonists and antagonists of RXFP3 to aid relaxin-3/RXFP3 research. 27498038
2017-05-13 20:18:00 the negatively charged transmembrane aspartate residue controls activation of the relaxin-3 receptor RXFP3 27353281

名称对应

Type IDs
Synonymous GPCR135, RLN3R1, RXFPR3, SALPR
Gene
UniProtKB-ID: RL3R1_HUMAN
UniprotKB: Q9NSD7
UniParc: UPI0000046AEB
EMBL: D88437, BC113438, AY394501, AY236541, BC113440
Ensembl: ENSG00000182631, ENSG00000277069
KO: hsa:51289
Nucleutide sequences
EMBL-CDS: AAI13439.1, BAA93001.1, AAI13441.1, AAQ92315.1, AAO92063.1
Ensembl_TRS: ENST00000616205, ENST00000330120
Protein sequencees
Ensembl_PRO: ENSP00000328708, ENSP00000480733
RefSeq: NP_057652.1
Others
UniRef100: UniRef100_Q9NSD7
UniRef90: UniRef90_Q9NSD7
UniRef50: UniRef50_Q9NSD7
UniGene: Hs.170146
CCDS: CCDS3900.1

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

Howard Florey Institute

2
2

Monash Institute of Pharmaceutical Sciences

2
3

College of Life Sciences and Technology

2
4

University College London

1
5

University of Regina

1
热点人员
排名 研究人员 文献
1

Roger J Summers

4
2

Ross A D Bathgate

4
3

John D Wade

4
4

Zeng-Guang Xu

4
5

Xiao-Xia Shao

4
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