| Type | Description |
|---|---|
| Definition | immediate early response 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:29:00 | Novel role of PAF1 in attenuating radiosensitivity in cervical cancer by inhibiting IER5 transcription. | 32471508 |
| 2021-03-20 13:32:00 | IER5, a DNA damage response gene, is required for Notch-mediated induction of squamous cell differentiation. | 32936072 |
| 2020-07-18 10:54:00 | Nuclear localization signal at amino acids 217-244 mediates complex formation with importin-alpha and importin-beta. NLS is essential for HSF1 dephosphorylation and full activation by IER5. | 31669744 |
| 2020-04-11 11:05:00 | The results suggest that IER2, IER5, and IER5L proteins are target protein-specific regulators of PP2A (protein phosphatase 2A) activity and modulate cell proliferation through CDC25A (cell division cycle 25A protein) activity. | 30599213 |
| 2018-06-23 11:42:00 | Observations suggest that IER5 is a novel regulator of the non-homologous end-joining pathway pathway for DNA double-strand breaks repair, possibly through its interaction with and Ku70. | 29104487 |
| Type | IDs |
|---|---|
| Synonymous | SBBI48 |
| Gene |
UniProtKB-ID:
IER5_HUMAN
UniprotKB:
Q5VY09
UniParc:
UPI000013E1C9
EMBL:
AF258581,
AK314830,
AJ251089,
BC000128,
AL356267,
AF178984
Ensembl:
ENSG00000162783
KO:
hsa:51278
|
| Nucleutide sequences |
EMBL-CDS:
AAF44348.1,
CAB91983.1,
AAH00128.1,
BAG37350.1,
AAG23784.1
Gene_ORFName:
SBBI48,
PP4583
Ensembl_TRS:
ENST00000367577
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356549
RefSeq:
NP_057629.2
|
| Others |
UniRef100:
UniRef100_Q5VY09
UniRef90:
UniRef90_Q5VY09
UniRef50:
UniRef50_Q5VY09
UniGene:
Hs.15725
CCDS:
CCDS1343.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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