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51274 KLF3

51274

KLF3

Kruppel like factor 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition Kruppel like factor 3

研究结论

Date Results Publications
2020-12-19 13:41:00 LncRNA NEAT1/miR-1224/KLF3 contributes to cell proliferation, apoptosis and invasion in lung cancer. 31646570
2020-01-25 12:55:00 bioinformatics analysis and in vitro experiments indicated that the role of KLF3 in lung cancer metastasis is dependent on the signaling pathway. Overall, our data indicated the crucial function of KLF3 in lung cancer metastasis and suggested opportunities to improve the therapy of patients with lung cancer. 31486564
2019-04-20 11:43:00 These data demonstrate that miR-326/Sp1/KLF3 regulatory axis is involved in the development of lung cancer. miR-326 could bind to 3'UTR of Sp1 but not KLF3 and decreased the accumulation of Sp1, which further indirectly reduced KLF3 expression and inactivated and PI3K/AKT signaling pathways in vitro and in vivo. 30485570
2017-10-14 10:28:00 Low KLF3 expression is associated with colorectal cancer. 28423541
2016-06-11 11:41:00 Among the mechanosensitive genes, the two transcription factors, HoxA5 and Klf3, contain cAMP-response-elements methylation of which could serve as a mechanosensitive master switch in gene expression in atherosclerosis. (Review) 25979369

名称对应

Type IDs
Synonymous BKLF
Gene
UniProtKB-ID: KLF3_HUMAN
UniprotKB: P57682
UniParc: UPI000020AFAA, UPI000012DED5
EMBL: AF285837, AB024523, BC051687, BC030662
Ensembl: ENSG00000109787
KO: hsa:51274
Nucleutide sequences
EMBL-CDS: BAA92271.1, AAH51687.1, AAH30662.1, AAK27329.1
Ensembl_TRS: ENST00000514033, ENST00000261438
Protein sequencees
Ensembl_PRO: ENSP00000421252, ENSP00000261438
RefSeq: XP_016863768.1, NP_057615.3
Others
UniRef100: UniRef100_P57682
UniRef90: UniRef90_P57682
UniRef50: UniRef50_P57682
UniGene: Hs.298658
CCDS: CCDS3444.1

全选

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研究热度

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