| Type | Description |
|---|---|
| Definition | proprotein convertase subtilisin/kexin type 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:50:00 | Revisiting Proinsulin Processing: Evidence That Human beta-Cells Process Proinsulin With Prohormone Convertase (PC) 1/3 but Not PC2. | 32291281 |
| 2020-10-24 14:11:00 | PCSK2 expression in neuroendocrine tumors points to a midgut, pulmonary, or pheochromocytoma-paraganglioma origin. | 32794589 |
| 2016-10-01 10:09:00 | PCSK2 gene polymorphisms are associated with pleiotropic effects on various traits of glucose homeostasis and incident diabetes. | 26607656 |
| 2016-04-02 11:04:00 | FAM20C plays a role in 7B2-mediated proPC2 activation by phosphorylating residue Thr111; and that 7B2 function is regulated by alternative splicing. | 25811241 |
| 2014-01-18 11:56:00 | in the processing of hypothalamic neuropeptides in huntington disease may partially arise from decreased PC1/3 and PC2 expressions. | 24226266 |
| Type | IDs |
|---|---|
| Synonymous | NEC 2, NEC-2, NEC2, PC2, SPC2 |
| Gene |
UniProtKB-ID:
NEC2_HUMAN
UniprotKB:
P16519
UniParc:
UPI0000000C6E,
UPI00017A6F60,
UPI0000206A6E
EMBL:
J05252,
M95961,
M95971,
AL031675,
AL031664,
M95962,
AK294200,
M95965,
M95969,
BC005815,
M95963,
M95960,
M95970,
M95968,
M95967,
M95966,
S75955,
BC040546,
M95964,
AL121779,
CH471133,
AL359511,
AK312341
Ensembl:
ENSG00000125851
KO:
hsa:5126
|
| Nucleutide sequences |
EMBL-CDS:
BAG57514.1,
AAD14202.1,
EAX10280.1,
EAX10281.1,
BAG35262.1,
EAX10279.1,
AAA60032.1,
AAH40546.1,
AAA59919.1,
AAH05815.1
Ensembl_TRS:
ENST00000262545,
ENST00000377899,
ENST00000536609
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000437458,
ENSP00000262545,
ENSP00000367131
RefSeq:
NP_001188457.1,
NP_002585.2,
NP_001188458.1
|
| Others |
UniRef100:
UniRef100_P16519
UniRef90:
UniRef90_P16519
UniRef50:
UniRef50_P16519
UniGene:
Hs.315186
CCDS:
CCDS13125.1,
CCDS56179.1,
CCDS56180.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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