| Type | Description |
|---|---|
| Definition | PHD finger protein 20 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-07 12:05:00 | PHF20 interacts with poly(ADP-ribose) polymerase 1 and directly binds to promoter regions of octamer-binding transcription factor 4 (OCT4) and sex determining region Y-box 2 (SOX2) to modulate a histone mark associated with active transcription, trimethylation of lysine 4 on histone H3 protein subunit (H3K4me3). | 29452418 |
| 2017-11-26 01:38:00 | These findings establish a unique PHF20-mediated link between MOF histone acetyltransferase (HAT), p53, and dimethylated lysine 4 of histone H3, and suggest a model for rapid spreading of H4K16ac-enriched open chromatin. | 27760318 |
| 2016-12-17 10:53:00 | PHF20 may play an important role in Non-small-cell lung cancer (NSCLC). | 26722404 |
| 2016-07-30 11:47:00 | Along with the PHF20/MOF complex, G9a links the crosstalk between ERalpha methylation and histone acetylation that governs the epigenetic regulation of hormonal gene expression. | 26960573 |
| 2014-10-11 11:00:00 | suggests a del(20q)-independent decrease in PHF20 expression in primary myelofibrosis | 24675105 |
| Type | IDs |
|---|---|
| Synonymous | C20orf104, GLEA2, HCA58, NZF, TDRD20A, TZP |
| Gene |
UniProtKB-ID:
PHF20_HUMAN
UniprotKB:
Q9BVI0
UniParc:
UPI000006FC22,
UPI000006E61B
EMBL:
AF220416,
CH471077,
AY027523,
BC048210,
BC150178,
AL109965,
BC093405,
AK314503,
BC080598,
AF258787,
AL078461,
AF348207
Ensembl:
ENSG00000025293
KO:
hsa:51230
|
| Nucleutide sequences |
EMBL-CDS:
AAH48210.1,
AAH93405.1,
EAW76153.1,
AAG49888.1,
EAW76157.1,
BAG37103.1,
AAH80598.1,
AAI50179.1,
AAK19748.1,
EAW76156.1,
EAW76155.1,
AAF34184.1,
AAK13046.1
Ensembl_TRS:
ENST00000374012
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363124
RefSeq:
XP_005260478.1,
XP_024307657.1,
XP_016883357.1,
XP_016883358.1,
XP_016883359.1,
XP_011527145.1,
XP_024307658.1,
NP_057520.2,
XP_011527146.1,
XP_016883360.1
|
| Others |
UniRef100:
UniRef100_Q9BVI0
UniRef90:
UniRef90_Q9BVI0
UniRef50:
UniRef50_Q9BVI0
UniGene:
Hs.517044
CCDS:
CCDS13268.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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