| Type | Description |
|---|---|
| Definition | carboxypeptidase A4 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:42:00 | Carboxypeptidase A4 promotes cardiomyocyte hypertrophy through activating PI3K-AKT-mTOR signaling. | 32347291 |
| 2020-06-06 10:26:00 | Findings suggest that the angiotensin II (Ang II) generation from hAng-(1-12) is primarily mediated by chymase rather than carboxypeptidase A (CPA). | 31466718 |
| 2020-02-01 13:08:00 | CPA4 promotes CRC cell growth via activating the and ERK pathways and may be a prognostic factor or therapeutic target for CRC | 31279884 |
| 2020-01-25 13:14:00 | we revealed that CPA4 downregulation may induce apoptosis and G1-S arrest by suppressing the protein kinase B/c-MYC pathway. These results suggest that CPA4 has an oncogenic effect on lung cancer growth. Taken together, we identified a novel gene in lung cancer that might provide a basis for new therapeutic targets. | 31397502 |
| 2018-02-24 11:17:00 | Serum CPA4 concentration combined with lymph node involvement may be used as accurate predictors of liver metastasis in colorectal cancer. | 27780921 |
| Type | IDs |
|---|---|
| Synonymous | CPA3 |
| Gene |
UniProtKB-ID:
CBPA4_HUMAN,
A4D1M3_HUMAN
UniprotKB:
Q9UI42,
A4D1M3
UniParc:
UPI000020FAA9,
UPI0000048F00
EMBL:
BC052289,
AC024085,
AK298550,
AK290993,
AY358699,
AF095719,
CH471070,
CH236950
Ensembl:
ENSG00000128510
KO:
hsa:51200
|
| Nucleutide sequences |
EMBL-CDS:
BAH12812.1,
AAQ89062.1,
AAH52289.1,
AAF23230.1,
EAL24091.1,
BAF83682.1,
EAW83753.1,
EAW83752.1
Gene_ORFName:
UNQ694/PRO1339,
hCG_18973,
tcag7.359
Ensembl_TRS:
ENST00000445470,
ENST00000222482
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000222482,
ENSP00000412947
RefSeq:
NP_001156918.1,
NP_057436.2
|
| Others |
UniRef100:
UniRef100_Q9UI42
UniRef90:
UniRef90_Q9UI42
UniRef50:
UniRef50_Q9UI42
UniGene:
Hs.93764
CCDS:
CCDS5818.1,
CCDS55163.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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