| Type | Description |
|---|---|
| Definition | pleckstrin homology domain containing O1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:27:00 | High expression of the CKIP-1 gene might promote apoptosis through downregulation of the Ras/ERK signalling pathway in the intestinal type of gastric cancer. | 32223671 |
| 2020-07-04 12:53:00 | CKIP-1 could interact with Neuropilin-1 (NRP1). | 29852799 |
| 2020-04-18 10:09:00 | The molecular functions of CKIP-1 in cell morphology, cell differentiation and cell apoptosis, the involved biological processes including bone formation, tumorigenesis and immune regulation are REVIEWED. The potential role of CKIP-1 in the treatment of human diseases such as osteoporosis, tumor, and atherosclerosis is indicated. | 31082489 |
| 2020-01-04 10:06:00 | mechanistic investigations suggested that CKIP-1 sharply suppressed the activity of AKT by inhibiting the phosphorylation, markedly downregulated the phosphorylated GSK3beta at Ser9, and promoted beta-catenin degradation. | 31355268 |
| 2019-10-05 10:44:00 | The results showed that PLEKHO1 knockdown significantly inhibited cell viability and facilitated apoptosis in vitro and impaired tumour formation in vivo. | 31180521 |
| Type | IDs |
|---|---|
| Synonymous | CKIP-1, CKIP1, JBP, OC120 |
| Gene |
UniProtKB-ID:
PKHO1_HUMAN,
Q5T4P9_HUMAN
UniprotKB:
Q53GL0,
Q5T4P9
UniParc:
UPI00015E0FB6,
UPI000020416C,
UPI000006DFAC
EMBL:
AF291105,
AF073836,
AF192912,
BC010149,
BC023533,
AK222921,
AC242988,
AL358073,
AF217956,
CH471121,
AF168676
Ensembl:
ENSG00000023902
KO:
hsa:51177
|
| Nucleutide sequences |
EMBL-CDS:
AAK71509.1,
AAH10149.1,
CAI14264.1,
AAF89644.1,
AAQ13826.1,
AAF13461.1,
BAD96641.1,
AAK28027.1,
EAW53580.1,
AAH23533.2,
CAI14262.1,
EAW53582.1
Gene_ORFName:
HQ0024c,
hCG_39382,
RP11-458I7.3-002
Ensembl_TRS:
ENST00000369124,
ENST00000369126
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358120,
ENSP00000358122
RefSeq:
NP_057358.2,
NP_001291653.1,
XP_016856909.1,
XP_024303246.1,
NP_001291651.1,
NP_001291652.1
|
| Others |
UniRef100:
UniRef100_Q53GL0
UniRef90:
UniRef90_Q53GL0
UniRef50:
UniRef50_Q53GL0
UniGene:
Hs.438824
CCDS:
CCDS945.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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