| Type | Description |
|---|---|
| Definition | hydroxysteroid 17-beta dehydrogenase 14 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-23 10:17:00 | Five new variants of HSD17B14 characterized by crystallography and enzyme kinetics. Tyr253' from the adjacent monomer ties the two monomers together. Disulfide bridge formed by Cys255 and Cys255' is not crucial for dimer stabilization. | 30836176 |
| 2013-01-12 10:02:00 | Results show that tumoural expression levels of 17betaHSD14 can predict the outcome of adjuvant tamoxifen treatment in terms of local recurrence-free survival in patients with lymph node-negative ER+ breast cancer. | 22792371 |
| 2010-01-21 00:00:00 | crystal structure of the DHRS10 apoenzyme exhibits secondary structure of the SDR (short-chain dehydrogenase/reductase) family | 17067289 |
| Type | IDs |
|---|---|
| Synonymous | DHRS10, SDR47C1, retSDR3 |
| Gene |
UniProtKB-ID:
DHB14_HUMAN,
A0A140VJH8_HUMAN
UniprotKB:
Q9BPX1,
A0A140VJH8
UniParc:
UPI000004FACC
EMBL:
BC006294,
AF126781,
HM005365,
BC006283,
AY358430
Ensembl:
ENSG00000087076
KO:
hsa:51171
|
| Nucleutide sequences |
EMBL-CDS:
AAH06283.1,
AAH06294.1,
AAQ88796.1,
AAF06940.1,
AEE60965.1
Gene_ORFName:
UNQ502/PRO474
Ensembl_TRS:
ENST00000263278
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263278
RefSeq:
XP_005259026.1,
XP_005259027.1,
NP_057330.2
|
| Others |
UniRef100:
UniRef100_Q9BPX1
UniRef90:
UniRef90_Q9BPX1
UniRef50:
UniRef50_Q9BPX1
UniGene:
Hs.18788
CCDS:
CCDS12736.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31515488 |
Nat Commun Robert Fragoza , Jishnu Das , Shayne D Wierbowski , Jin Liang , Tina N Tran , Siqi Liang , Juan F Beltran , Christen A Rivera-Erick , Kaixiong Ye , Ting-Yi Wang , Li Yao , Matthew Mort , Peter D Stenson , David N Cooper , Xiaomu Wei , Alon Keinan , John C Schimenti , Andrew G Clark , Haiyuan Yu |
2019-09-12 | - |
| 30836176 |
J. Steroid Biochem. Mol. Biol. Mohammed J Badran , Nicole Bertoletti , Aline Keils , Andreas Heine , Gerhard Klebe , Sandrine Marchais-Oberwinkler |
2019-05-01 | - |
| 29892012 |
Nat Genet Siwei Chen , Robert Fragoza , Lambertus Klei , Yuan Liu , Jiebiao Wang , Kathryn Roeder , Bernie Devlin , Haiyuan Yu |
2018-07-01 | - |
| 28611215 |
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown |
2017-06-27 | - |
| 27107014 |
An inter-species protein-protein interaction network across vast evolutionary distance. Mol Syst Biol Quan Zhong , Samuel J Pevzner , Tong Hao , Yang Wang , Roberto Mosca , Jörg Menche , Mikko Taipale , Murat TaÅan , Changyu Fan , Xinping Yang , Patrick Haley , Ryan R Murray , Flora Mer , Fana Gebreab , Stanley Tam , Andrew MacWilliams , Amélie Dricot , Patrick Reichert , Balaji Santhanam , Lila Ghamsari , Michael A Calderwood , Thomas Rolland , Benoit Charloteaux , Susan Lindquist , Albert-László Barabási , David E Hill , Patrick Aloy , Michael E Cusick , Yu Xia , Frederick P Roth , Marc Vidal |
2016-04-22 | - |
| 27107012 |
Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Mol Syst Biol Nozomu Yachie , Evangelia Petsalaki , Joseph C Mellor , Jochen Weile , Yves Jacob , Marta Verby , Sedide B Ozturk , Siyang Li , Atina G Cote , Roberto Mosca , Jennifer J Knapp , Minjeong Ko , Analyn Yu , Marinella Gebbia , Nidhi Sahni , Song Yi , Tanya Tyagi , Dayag Sheykhkarimli , Jonathan F Roth , Cassandra Wong , Louai Musa , Jamie Snider , Yi-Chun Liu , Haiyuan Yu , Pascal Braun , Igor Stagljar , Tong Hao , Michael A Calderwood , Laurence Pelletier , Patrick Aloy , David E Hill , Marc Vidal , Frederick P Roth |
2016-04-22 | - |
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 25910212 |
Widespread macromolecular interaction perturbations in human genetic disorders. Cell Nidhi Sahni , Song Yi , Mikko Taipale , Juan I Fuxman Bass , Jasmin Coulombe-Huntington , Fan Yang , Jian Peng , Jochen Weile , Georgios I Karras , Yang Wang , István A Kovács , Atanas Kamburov , Irina Krykbaeva , Mandy H Lam , George Tucker , Vikram Khurana , Amitabh Sharma , Yang-Yu Liu , Nozomu Yachie , Quan Zhong , Yun Shen , Alexandre Palagi , Adriana San-Miguel , Changyu Fan , Dawit Balcha , Amelie Dricot , Daniel M Jordan , Jennifer M Walsh , Akash A Shah , Xinping Yang , Ani K Stoyanova , Alex Leighton , Michael A Calderwood , Yves Jacob , Michael E Cusick , Kourosh Salehi-Ashtiani , Luke J Whitesell , Shamil Sunyaev , Bonnie Berger , Albert-László Barabási , Benoit Charloteaux , David E Hill , Tong Hao , Frederick P Roth , Yu Xia , Albertha J M Walhout , Susan Lindquist , Marc Vidal |
2015-04-23 | - |
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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