| Type | Description |
|---|---|
| Definition | debranching RNA lariats 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 13:23:00 | findings support a new view of the early steps in HIV genome replication - they support a model in which lariat formation of viral genomic RNA is important for minus-strand transfer, with DBR1 being required to resolve the lariat to allow reverse transcription to proceed | 28931690 |
| 2017-10-14 11:24:00 | Transcriptomic sequencing confirmed the effect of hDBR1 on RNA splicing, and metabolite profiling supported the observation that neoplasm is triggered by a decrease in hDBR1 expression both in vitro and in vivo. | 28504715 |
| 2017-01-14 10:20:00 | saturation mutagenesis of DBR1 and Gal4 and show that the experimental phenotypes for over 80% of the mutations correlate well with predicted effects of mutations on protein stability and RNA binding affinity. | 26797105 |
| 2015-10-03 10:32:00 | Results of protein-protein interaction between human Dbr1 and factors found in the Intron Large complex identify Xab2 and a novel protein CWF19L1 as specific interactors of DBR1. | 25671812 |
| 2014-10-04 10:52:00 | Inhibition of DBR1 caused a significant reduction in the formation of intermediate and full-length HIV-1 cDNA. | 24672043 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DBR1_HUMAN
UniprotKB:
Q9UK59
UniParc:
UPI000020A301,
UPI000006DFC5
EMBL:
AK000116,
AF180919,
BC009472
Ensembl:
ENSG00000138231
KO:
hsa:51163
|
| Nucleutide sequences |
EMBL-CDS:
AAD53327.2,
AAH09472.1,
BAA90954.1
Ensembl_TRS:
ENST00000260803
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000260803
RefSeq:
NP_057300.2
|
| Others |
UniRef100:
UniRef100_Q9UK59
UniRef90:
UniRef90_Q9UK59
UniRef50:
UniRef50_Q9UK59
UniGene:
Hs.477700
CCDS:
CCDS33863.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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