| Type | Description |
|---|---|
| Definition | pericentrin |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:34:00 | Centriole-independent mitotic spindle assembly relies on the PCNT-CDK5RAP2 pericentriolar matrix. | 33170211 |
| 2021-02-02 13:24:00 | Microcephalic osteodysplastic primordial dwarfism type II: Additional nine patients with implications on phenotype and genotype correlation. | 32267100 |
| 2020-07-18 10:53:00 | Deletion of PCNT in HeLa cells had little effect on interphase centrosomes. However, centrioles in PCNT-deleted mitotic cells prematurely separated and frequently amplified, revealing that centrioles are limited within the spindle poles by PCNT during mitosis. | 30814333 |
| 2019-12-07 10:48:00 | Critical homozygous or compound heterozygous variants in PCNT are a known cause of microcephalic osteodysplastic primordial dwarfism type II accompanied by mandibular hypoplasia, which is similar to the maxillofacial phenotype. | 31311520 |
| 2019-11-30 11:44:00 | CRISPR/Cas9-mediated knockout of Syne-2 in cell culture led to an overexpression and mislocalization of Pcnt and to ciliogenesis defects. This suggests that the Pcnt-Syne-2 complex is important for ciliogenesis and outer segment formation during retinal development and plays a role in nuclear migration. | 30054381 |
| Type | IDs |
|---|---|
| Synonymous | KEN, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4 |
| Gene |
UniProtKB-ID:
PCNT_HUMAN
UniprotKB:
O95613
UniParc:
UPI0001E88ECA,
UPI00001AEB88
EMBL:
AB007862,
AF515282,
AP000337,
AP000471,
AP001477,
AP000335,
AK093923,
U52962,
AP000336
Ensembl:
ENSG00000160299
KO:
hsa:5116
|
| Nucleutide sequences |
EMBL-CDS:
AAP46636.1,
BAC04252.1,
AAD10838.1,
BAA23698.3
Ensembl_TRS:
ENST00000359568
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000352572
RefSeq:
XP_005261181.1,
NP_001302458.1,
XP_011527896.1,
NP_006022.3,
XP_016883852.1,
XP_016883851.1,
XP_024307851.1,
XP_024307850.1
|
| Others |
UniRef100:
UniRef100_O95613
UniRef90:
UniRef90_O95613
UniRef50:
UniRef50_O95613
UniGene:
Hs.474069
CCDS:
CCDS33592.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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