| Type | Description |
|---|---|
| Definition | serpin family A member 10 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 10:15:00 | these results suggest an important anticoagulant role for the ZPI-PZ complex in regulating both free FXa generated in the initiation phase of coagulation as well as prothrombinase-bound FXa in the propagation phase that complement prothrombinase regulation by APC. | 30918026 |
| 2018-06-16 10:49:00 | PZ/ZPI polymorphisms do not appear to play an active role in the development of prosthesis heart valve thrombosis. | 29302946 |
| 2017-09-30 13:56:00 | Data suggest oxidized lipid vesicles with phosphatidylserine/polyunsaturated fatty acids promote inactivation of ZPI-PZ complex or free ZPI; binding of PZ-complexed or free ZPI to oxidized vesicles mediates inactivation of ZPI (an inhibitor of FXa); blocking heparin- (anticoagulant-)binding site on ZPI interferes with binding to lipid or PZ. (ZPI = protein Z-dependent protease inhibitor; PZ = protein Z; FXa = factor Xa) | 28717005 |
| 2016-07-30 11:48:00 | rs2232710 SNV showed no association with DVT in two Dutch replication cohorts the LETS study and the MEGA study, indicating that the rs2232710 variant is not a risk factor for DVT | 26982741 |
| 2015-06-27 10:16:00 | Results show the energetic basis of the Z-dependent protease inhibitor (ZPI)-protein Z (PZ) interaction and suggest an important role for ZPI Lys-239 in PZ catalytic action. | 25713144 |
| Type | IDs |
|---|---|
| Synonymous | PZI, ZPI |
| Gene |
UniProtKB-ID:
ZPI_HUMAN,
A0A024R6I6_HUMAN,
G3V2W1_HUMAN
UniprotKB:
Q9UK55,
A0A024R6I6,
G3V2W1
UniParc:
UPI000013C46E,
UPI000059D298
EMBL:
BC022261,
EF621762,
AL117259,
AY358597,
BX248011,
CH471061,
AF181467
Ensembl:
ENSG00000278767,
ENSG00000140093
KO:
hsa:51156
|
| Nucleutide sequences |
EMBL-CDS:
ABR09269.1,
AAH22261.1,
AAQ88960.1,
CAD62339.1,
AAD53962.1,
EAW81566.1,
EAW81565.1,
EAW81564.1
Gene_ORFName:
UNQ707/PRO1358,
hCG_22331,
hCG_22331
Ensembl_TRS:
ENST00000554173,
ENST00000261994,
ENST00000393096,
ENST00000614630,
ENST00000616057,
ENST00000554723
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000450971,
ENSP00000484632,
ENSP00000261994,
ENSP00000376809,
ENSP00000450896,
ENSP00000482029
RefSeq:
NP_057270.1,
XP_016876842.1,
XP_005267790.1,
NP_001094077.1
|
| Others |
UniRef100:
UniRef100_Q9UK55
UniRef90:
UniRef90_Q9UK55
UniRef50:
UniRef50_Q9UK55
UniGene:
Hs.118620
CCDS:
CCDS9923.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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