| Type | Description |
|---|---|
| Definition | insulin induced gene 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:35:00 | A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. | 33446483 |
| 2021-03-27 14:43:00 | The CC Genotype of Insulin-Induced Gene 2 rs7566605 Is a Protective Factor of Hypercholesteremia Susceptible to Mild Cognitive Impairment, Especially to the Executive Function of Patients with Type 2 Diabetes Mellitus. | 32596317 |
| 2021-02-20 13:31:00 | Insulin-Induced Gene 2 Expression Is Associated with Breast Cancer Metastasis. | 33321090 |
| 2020-06-06 12:45:00 | the gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis; findings highlight the importance of the protein kinase activity of PCK1 in the activation of SREBPs, lipogenesis and the development of hepatocellular carcinoma | 32322062 |
| 2020-01-11 11:59:00 | polymorphism rs7566605 of the INSIG2 gene is associated with higher triglycerides levels and blood pressure values, which are also considered as risk factors for the development of metabolic syndrome | 31144980 |
| Type | IDs |
|---|---|
| Synonymous | INSIG-2 |
| Gene |
UniProtKB-ID:
INSI2_HUMAN,
B4DQ23_HUMAN,
A0A024RAI2_HUMAN
UniprotKB:
Q9Y5U4,
B4DQ23,
A0A024RAI2
UniParc:
UPI0000207DF7,
UPI0000073C50
EMBL:
BC022475,
AK291433,
AF125392,
AC009303,
AF527632,
CH471103,
AK298599
Ensembl:
ENSG00000125629
KO:
hsa:51141
|
| Nucleutide sequences |
EMBL-CDS:
AAH22475.1,
BAF84122.1,
EAW95199.1,
AAX93280.1,
AAN28333.1,
AAD43048.1,
BAG60785.1,
EAW95200.1
Gene_ORFName:
hCG_1686419
Ensembl_TRS:
ENST00000245787
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000245787
RefSeq:
NP_057217.2,
NP_001308262.1,
NP_001308258.1,
NP_001308261.1,
NP_001308259.1,
NP_001308260.1
|
| Others |
UniRef100:
UniRef100_Q9Y5U4,
UniRef100_B4DQ23
UniRef90:
UniRef90_B4DQ23,
UniRef90_Q9Y5U4
UniRef50:
UniRef50_Q9Y5U4,
UniRef50_Q8BGI3
UniGene:
Hs.7089
CCDS:
CCDS2122.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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