| Type | Description |
|---|---|
| Definition | secretion associated Ras related GTPase 1B |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:28:00 | Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly. | 32358066 |
| 2020-06-27 11:15:00 | SAR1B GTPase is necessary to protect intestinal cells from disorders of lipid homeostasis, oxidative stress, and inflammation | 31409740 |
| 2020-06-06 13:35:00 | Chylomicron retention disease is an autosomal recessive disorder, in which intestinal fat malabsorption is the main cause of diverse severe manifestations due to mutations in the SAR1B. (Review) | 30640893 |
| 2020-05-16 10:46:00 | Twenty-three patients were genetically confirmed as affected by primary hypobetalipoproteinemia. In this group of patients, the most prevalent mutated genes were APOB (in 17 patients, with eight novel mutations identified), SAR1B (in 3 patients, with one novel mutation identified), ANGPTL3 (in 2 patients), and MTTP (in 1 patient). The other 21 patients could not be genetically diagnosed with hypobetalipoproteinemia despit | 30782561 |
| 2018-12-22 11:21:00 | Study data suggest that SAR1A and SAR1B are the critical regulators of trafficking of Nav1.5. Moreover, SAR1A and SAR1B interact with MOG1, and are required for MOG1-mediated cell surface expression and function of Nav1.5. | 30251687 |
| Type | IDs |
|---|---|
| Synonymous | ANDD, CMRD, GTBPB, SARA2 |
| Gene |
UniProtKB-ID:
SAR1B_HUMAN
UniprotKB:
Q9Y6B6
UniParc:
UPI0000135569
EMBL:
BC002847,
AF092130,
CH471062,
AF087850,
BC093034
Ensembl:
ENSG00000152700
KO:
hsa:51128
|
| Nucleutide sequences |
EMBL-CDS:
AAD40372.1,
AAH02847.1,
EAW62249.1,
AAP97161.1,
EAW62250.1,
AAH93034.1
Ensembl_TRS:
ENST00000439578,
ENST00000402673
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000385432,
ENSP00000404997
RefSeq:
NP_057187.1,
NP_001028675.1
|
| Others |
UniRef100:
UniRef100_Q9Y6B6
UniRef90:
UniRef90_Q9Y6B6
UniRef50:
UniRef50_Q9Y6B6
UniGene:
Hs.432984
CCDS:
CCDS4177.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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