| Type | Description |
|---|---|
| Definition | tripartite motif containing 17 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 12:08:00 | overexpression of TRIM28 or knock-out of TRIM17 reduced BCLA1 protein levels and restored sensitivity of melanoma cells to BRAF-targeted therapy. Therefore, our data describe a molecular rheostat in which two proteins of the TRIM family antagonistically regulate BCL2A1 stability and modulate cell death. | 30042493 |
| 2020-02-29 10:48:00 | data suggest LSD1 largely plays a tumor suppressor role in luminal breast cancer and the oncogenic program associated with LSD1-inhibition may be suppressed via TRIM37-inhibition | 31409898 |
| 2019-12-14 12:06:00 | deregulation of the TRIM17/TRIM41/ZSCAN21 pathway may be involved in the pathogenesis of Parkinson's disease. | 30485814 |
| 2017-08-05 12:57:00 | TRIM17 promoted the removal of midbodies, remnants of the cell division machinery that are known autophagy targets. | 27562068 |
| 2015-08-08 11:14:00 | NFATc3 interacted in a SUMO-dependent manner with Trim17, an E3 ubiquitin ligase necessary for neuronal apoptosis | 25215946 |
| Type | IDs |
|---|---|
| Synonymous | RBCC, RNF16, terf |
| Gene |
UniProtKB-ID:
TRI17_HUMAN,
B3KP04_HUMAN,
A0A024R3R3_HUMAN
UniprotKB:
Q9Y577,
B3KP04,
A0A024R3R3
UniParc:
UPI00017A7FA2,
UPI000000163B,
UPI000048ACD6
EMBL:
BC033788,
AL670729,
AF156271,
AK301105,
CH471098,
AL139288,
AK055426
Ensembl:
ENSG00000162931,
ENSG00000285344
KO:
hsa:51127
|
| Nucleutide sequences |
EMBL-CDS:
BAG62704.1,
AAD40286.1,
AAH33788.1,
EAW69876.1,
EAW69874.1,
BAG51516.1,
EAW69872.1,
EAW69875.1,
EAW69873.1
Gene_ORFName:
hCG_42238,
hCG_42238
Ensembl_TRS:
ENST00000366698,
ENST00000645958,
ENST00000646778,
ENST00000295033,
ENST00000645562,
ENST00000456946,
ENST00000647385,
ENST00000366697
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000403312,
ENSP00000493891,
ENSP00000496098,
ENSP00000355659,
ENSP00000295033,
ENSP00000494586,
ENSP00000355658,
ENSP00000495842
RefSeq:
XP_006711842.1,
XP_016856908.1,
NP_001128327.1,
XP_011542513.1,
XP_011542511.1,
XP_011542512.1,
NP_001020111.1,
NP_057186.1
|
| Others |
UniRef100:
UniRef100_B3KP04,
UniRef100_Q9Y577
UniRef90:
UniRef90_Q9Y577,
UniRef90_A0A0D9RVG9
UniRef50:
UniRef50_Q9Y577,
UniRef50_A0A0D9RVG9
UniGene:
Hs.121748
CCDS:
CCDS44327.1,
CCDS1571.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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