| Type | Description |
|---|---|
| Definition | lysine methyltransferase 5B |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:06:00 | Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich's ataxia patient cells. | 33028632 |
| 2020-06-13 11:39:00 | SUV420H1 is a protein lysine methyltransferase that introduces di- and trimethylation of H4K20 and is frequently mutated in human cancers. Somatic Cancer Mutations in the SUV420H1 Protein Lysine Methyltransferase Modulate Its Catalytic Activity. | 31255706 |
| 2018-01-27 11:08:00 | epsilon-globin expression is regulated by SUV4-20h1. | 26802048 |
| 2017-09-30 12:13:00 | Altogether, these results reveal Suv4-20h-mediated histone H4K20 tri-methylation as a critical determinant in the selection of active replication initiation sites in heterochromatin regions of mammalian genomes. | 28778956 |
| 2016-10-08 11:43:00 | overexpression of SUV420H1 may result in activation of the ERK signaling pathway | 26586479 |
| Type | IDs |
|---|---|
| Synonymous | CGI-85, CGI85, MRD51, SUV420H1 |
| Gene |
UniProtKB-ID:
KMT5B_HUMAN,
B7WNX0_HUMAN,
B7Z5N2_HUMAN
UniprotKB:
Q4FZB7,
B7WNX0,
B7Z5N2
UniParc:
UPI0004620AD3,
UPI00003FF22C,
UPI0001891755,
UPI0001914DA9,
UPI00002335FB
EMBL:
BC104483,
BC002522,
BC098121,
BC065287,
KC877427,
BC012933,
BC087834,
AF151843,
BC103498,
AK000046,
AF264782,
BC099714,
KC877429,
AK299201,
AL512763,
AP002992
Ensembl:
ENSG00000110066
KO:
hsa:51111
|
| Nucleutide sequences |
EMBL-CDS:
BAA90905.1,
AAH98121.1,
AAH65287.1,
AAH87834.1,
CAC21680.1,
AAG36937.1,
AAH12933.2,
AAH02522.2,
AAH99714.1,
AAI03499.1,
AAD34080.1,
AAI04484.1,
BAH12968.1
Gene_ORFName:
CGI-85
Ensembl_TRS:
ENST00000405515,
ENST00000441488,
ENST00000401547,
ENST00000304363,
ENST00000615954,
ENST00000402185
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000411146,
ENSP00000385640,
ENSP00000484858,
ENSP00000305899,
ENSP00000385965,
ENSP00000384724
RefSeq:
NP_001287837.1,
NP_001356359.1,
NP_001356360.1,
NP_001356362.1,
XP_011543394.1,
NP_001356355.1,
NP_001287836.1,
NP_060105.3,
XP_016873367.1,
NP_001356358.1,
NP_057112.3,
XP_006718644.1,
NP_001356356.1,
NP_001287838.1,
NP_001356354.1,
NP_001356357.1,
XP_024304338.1,
NP_001356361.1,
NP_001350495.1,
XP_005274092.2,
XP_005274093.2,
NP_001356353.1
|
| Others |
UniRef100:
UniRef100_B7Z5N2,
UniRef100_B7WNX0,
UniRef100_Q4FZB7
UniRef90:
UniRef90_B7WNX0,
UniRef90_Q4FZB7
UniRef50:
UniRef50_Q4FZB7,
UniRef50_Q3U8K7-2
UniGene:
Hs.632120
CCDS:
CCDS44660.1,
CCDS31623.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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