| Type | Description |
|---|---|
| Definition | SID1 transmembrane family member 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 10:05:00 | this study found an association between metabolic syndrome and an intronic SNP pair, rs7107152 and rs1242229, in SIDT2 gene at 11q23.3. | 30382898 |
| 2019-02-23 13:03:00 | We concluded that Sidt2 deficiency leads to muscular dystrophy-like phenotype in mice and Sidt2 plays a critical role in the late stage of autophagy. | 29752955 |
| 2019-02-23 10:12:00 | In silico analysis identified SIDT1 and SIDT2 sharing identity and conserved cholesterol binding (CRAC) domains with C. elegans ChUP-1. Further evidence indicate that SIDT1 and SIDT2 not only do not transport RNA, but they are involved in cholesterol transport. Single point mutations in the CRAC domains of both proteins prevent FRET between SIDT1, SIDT2 and dehydroergosterol and alter cholesterol transport. | 28785058 |
| 2017-12-09 12:47:00 | SIDT2 (SID1 transmembrane family, member 2), an ortholog of the Caenorhabditis elegans putative RNA transporter SID-1 (systemic RNA interference defective-1), mediates RNA translocation during RNautophagy | 27846365 |
| 2017-05-27 10:49:00 | Sidt2 is located on chromosome 11q23, a locus repeatedly found by chromosomal mapping of Alzheimer's disease-related genes. | 27987306 |
| Type | IDs |
|---|---|
| Synonymous | CGI-40 |
| Gene |
UniProtKB-ID:
SIDT2_HUMAN
UniprotKB:
Q8NBJ9
UniParc:
UPI000004BA68,
UPI0000052B48
EMBL:
AY358442,
AF151799,
AK075471,
AK075137
Ensembl:
ENSG00000149577
KO:
hsa:51092
|
| Nucleutide sequences |
EMBL-CDS:
AAD34036.1,
BAC11427.1,
AAQ88807.1,
BAC11641.1
Gene_ORFName:
UNQ685/PRO1325,
CGI-40,
PSEC0072
Ensembl_TRS:
ENST00000620360,
ENST00000324225
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000314023,
ENSP00000482762
RefSeq:
NP_001035545.1
|
| Others |
UniRef100:
UniRef100_Q8NBJ9
UniRef90:
UniRef90_Q8CIF6-2
UniRef50:
UniRef50_Q8CIF6
UniGene:
Hs.712144
CCDS:
CCDS31682.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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