| Type | Description |
|---|---|
| Definition | TNNI3 interacting kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:27:00 | New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K). | 32272798 |
| 2020-12-31 11:06:00 | A heterozygous p.Thr539Ala mutation in TNNI3K, a cardiac-specific kinase, is the likely cause for a novel familial cardiac conduction disease (FCCD) | 25791106 |
| 2020-02-01 11:12:00 | we show that several common human TNNI3K kinase domain variants substantially compromise kinase activity, suggesting that TNNI3K may influence human heart regenerative capacity and potentially also other aspects of human heart disease. | 31589606 |
| 2019-06-22 11:48:00 | Results showed that TNNI3K was highly in cholangiocarcinoma (CCA) patients. Furthermore, TNNI3K-knockdown decreased the growth of CCA cell lines. | 30334579 |
| 2018-07-14 10:04:00 | results suggest that ACE2, TNNI3K and CALM3 polymorphisms are associated with increased risk of hypertrophic cardiomyopathies and dilated cardiomyopathies and may act as disease modifiers of these diseases. | 28744816 |
| Type | IDs |
|---|---|
| Synonymous | CARK, CCDD |
| Gene |
UniProtKB-ID:
TNI3K_HUMAN
UniprotKB:
Q59H18
UniParc:
UPI0000578E0C,
UPI0000578E0D,
UPI00005E2707,
UPI0000035B8F
EMBL:
AF116826,
AC119672,
AB208941,
BX470253,
CH471059,
AC105271,
BX640903,
BC117262,
BC032865,
AY303691,
DQ822519,
BC113539,
AC098692,
AC093158
Ensembl:
ENSG00000116783
KO:
hsa:100526835,
hsa:51086
|
| Nucleutide sequences |
EMBL-CDS:
AAI17263.1,
ABG46944.1,
EAX06415.1,
AAP72030.1,
AAD29632.1,
AAH32865.1,
BAD92178.1,
CAE45949.1,
AAI13540.1
Ensembl_TRS:
ENST00000326637
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000322251
RefSeq:
NP_057062.1
|
| Others |
UniRef100:
UniRef100_Q59H18
UniRef90:
UniRef90_Q59H18
UniRef50:
UniRef50_Q59H18
UniGene:
Hs.480085
CCDS:
CCDS664.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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