| Type | Description |
|---|---|
| Definition | nitric oxide synthase interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 11:21:00 | While NOSIP expression was increased in Hirschsprung's disease (HSCR) vs. non- HSCR patients, no significant difference was observed in patients with Hirschsprung's associated enterocolitis. The increased expression of NOSIP in the aganglionic and ganglionic bowel of HSCR may contribute to the development of enterocolitis by inhibiting local nitric oxide production in patients with Hirschsprung's disease. | 28196663 |
| 2010-01-21 00:00:00 | Endogenous NOSIP reduces the enzymatic capacity of eNOS, specifically in the G(2) phase of the cell cycle by targeting eNOS to the actin cytoskeleton. | 16135813 |
| 2001-05-17 06:30:00 | endothelial nitric oxide synthase (eNOS) interacting protein (NOSIP), modulator of eNOS activity by alteration of eNOS subcellular localisation; high expression levels in endothelial cells and vascularized tissue. | 11149895 |
| Type | IDs |
|---|---|
| Synonymous | CGI-25 |
| Gene |
UniProtKB-ID:
NOSIP_HUMAN,
A0A075B6F9_HUMAN
UniprotKB:
Q9Y314,
A0A075B6F9
UniParc:
UPI000006F7E8,
UPI0002A475CB
EMBL:
BC009299,
AF132959,
BC011249,
AC010619,
BC010077,
KF456600
Ensembl:
ENSG00000142546
KO:
hsa:51070
|
| Nucleutide sequences |
EMBL-CDS:
AAH09299.1,
AAH11249.1,
AAD27734.1,
AAH10077.1
Gene_ORFName:
CGI-25
Ensembl_TRS:
ENST00000596358,
ENST00000339093
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000470034,
ENSP00000343497
RefSeq:
XP_011525317.1,
NP_057037.1,
NP_001350578.1,
XP_016882340.1,
NP_001257889.1,
XP_024307298.1,
XP_011525319.1,
XP_024307297.1,
XP_016882341.1,
XP_024307296.1,
XP_005259021.1
|
| Others |
UniRef100:
UniRef100_A0A075B6F9,
UniRef100_Q9Y314
UniRef90:
UniRef90_Q9Y314,
UniRef90_Q4R7H4
UniRef50:
UniRef50_Q9Y314
UniGene:
Hs.7236
CCDS:
CCDS12772.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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