| Type | Description |
|---|---|
| Definition | calcium homeostasis modulator family member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 11:48:00 | Molecular dynamics simulations suggest that lipids can favorably assemble into a bilayer within the larger human CALHM2 pore, but not within chicken CALHM1, demonstrating the potential correlation between pore size, lipid accommodation and channel activity. | 31988524 |
| 2020-04-11 11:05:00 | shows that purified CALHM2 channels form both gap junctions and undecameric hemichannels | 31776515 |
| 2010-09-13 12:16:00 | This study failed to show an association between theeight SNPs of the CALHM2 genes and alzheimer disease. | 20164573 |
| 2010-04-07 21:40:00 | Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | 20164573 |
| 2009-12-02 21:41:00 | Observational study of gene-disease association. (HuGE Navigator) | 16385451 |
| Type | IDs |
|---|---|
| Synonymous | FAM26B |
| Gene |
UniProtKB-ID:
CAHM2_HUMAN
UniprotKB:
Q9HA72
UniParc:
UPI00001C0AD3,
UPI0000070F1F,
UPI0000070139
EMBL:
AK125276,
AL139339,
BC000039,
AF131810,
AK022195,
CH471066
Ensembl:
ENSG00000138172
KO:
hsa:51063
|
| Nucleutide sequences |
EMBL-CDS:
AAD20050.1,
BAB13983.1,
EAW49635.1,
EAW49637.1,
EAW49636.1,
AAH00039.1,
EAW49634.1,
EAW49638.1
Ensembl_TRS:
ENST00000260743,
ENST00000369788
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358803,
ENSP00000260743
RefSeq:
XP_006717947.1,
XP_016871798.1,
XP_016871796.1,
XP_016871797.1,
XP_024303802.1,
XP_016871795.1,
XP_011538150.1,
XP_006717943.1,
XP_006717946.1,
NP_057000.2,
XP_024303803.1
|
| Others |
UniRef100:
UniRef100_Q9HA72
UniRef90:
UniRef90_Q9HA72
UniRef50:
UniRef50_Q9HA72
UniGene:
Hs.241545
CCDS:
CCDS7549.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31988524 |
Structure and assembly of calcium homeostasis modulator proteins. Nat Struct Mol Biol Johanna L Syrjanen , Kevin Michalski , Tsung-Han Chou , Timothy Grant , Shanlin Rao , Noriko Simorowski , Stephen J Tucker , Nikolaus Grigorieff , Hiro Furukawa |
2020-02-01 | - |
| 31776515 |
The structures and gating mechanism of human calcium homeostasis modulator 2. Nature Wooyoung Choi , Nicolina Clemente , Weinan Sun , Juan Du , Wei Lü |
2019-12-01 | - |
| 23974872 |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet Stephan Ripke , Colm O'Dushlaine , Kimberly Chambert , Jennifer L Moran , Anna K Kähler , Susanne Akterin , Sarah E Bergen , Ann L Collins , James J Crowley , Menachem Fromer , Yunjung Kim , Sang Hong Lee , Patrik K E Magnusson , Nick Sanchez , Eli A Stahl , Stephanie Williams , Naomi R Wray , Kai Xia , Francesco Bettella , Anders D Borglum , Brendan K Bulik-Sullivan , Paul Cormican , Nick Craddock , Christiaan de Leeuw , Naser Durmishi , Michael Gill , Vera Golimbet , Marian L Hamshere , Peter Holmans , David M Hougaard , Kenneth S Kendler , Kuang Lin , Derek W Morris , Ole Mors , Preben B Mortensen , Benjamin M Neale , Francis A O'Neill , Michael J Owen , Milica Pejovic Milovancevic , Danielle Posthuma , John Powell , Alexander L Richards , Brien P Riley , Douglas Ruderfer , Dan Rujescu , Engilbert Sigurdsson , Teimuraz Silagadze , August B Smit , Hreinn Stefansson , Stacy Steinberg , Jaana Suvisaari , Sarah Tosato , Matthijs Verhage , James T Walters , Multicenter Genetic Studies of Schizophrenia Consortium , Douglas F Levinson , Pablo V Gejman , Kenneth S Kendler , Claudine Laurent , Bryan J Mowry , Michael C O'Donovan , Michael J Owen , Ann E Pulver , Brien P Riley , Sibylle G Schwab , Dieter B Wildenauer , Frank Dudbridge , Peter Holmans , Jianxin Shi , Margot Albus , Madeline Alexander , Dominique Campion , David Cohen , Dimitris Dikeos , Jubao Duan , Peter Eichhammer , Stephanie Godard , Mark Hansen , F Bernard Lerer , Kung-Yee Liang , Wolfgang Maier , Jacques Mallet , Deborah A Nertney , Gerald Nestadt , Nadine Norton , Francis A O'Neill , George N Papadimitriou , Robert Ribble , Alan R Sanders , Jeremy M Silverman , Dermot Walsh , Nigel M Williams , Brandon Wormley , Psychosis Endophenotypes International Consortium , Maria J Arranz , Steven Bakker , Stephan Bender , Elvira Bramon , David Collier , Benedicto Crespo-Facorro , Jeremy Hall , Conrad Iyegbe , Assen Jablensky , Rene S Kahn , Luba Kalaydjieva , Stephen Lawrie , Cathryn M Lewis , Kuang Lin , Don H Linszen , Ignacio Mata , Andrew McIntosh , Robin M Murray , Roel A Ophoff , John Powell , Dan Rujescu , Jim Van Os , Muriel Walshe , Matthias Weisbrod , Durk Wiersma , Wellcome Trust Case Control Consortium 2 , Peter Donnelly , Ines Barroso , Jenefer M Blackwell , Elvira Bramon , Matthew A Brown , Juan P Casas , Aiden P Corvin , Panos Deloukas , Audrey Duncanson , Janusz Jankowski , Hugh S Markus , Christopher G Mathew , Colin N A Palmer , Robert Plomin , Anna Rautanen , Stephen J Sawcer , Richard C Trembath , Ananth C Viswanathan , Nicholas W Wood , Chris C A Spencer , Gavin Band , Céline Bellenguez , Colin Freeman , Garrett Hellenthal , Eleni Giannoulatou , Matti Pirinen , Richard D Pearson , Amy Strange , Zhan Su , Damjan Vukcevic , Peter Donnelly , Cordelia Langford , Sarah E Hunt , Sarah Edkins , Rhian Gwilliam , Hannah Blackburn , Suzannah J Bumpstead , Serge Dronov , Matthew Gillman , Emma Gray , Naomi Hammond , Alagurevathi Jayakumar , Owen T McCann , Jennifer Liddle , Simon C Potter , Radhi Ravindrarajah , Michelle Ricketts , Avazeh Tashakkori-Ghanbaria , Matthew J Waller , Paul Weston , Sara Widaa , Pamela Whittaker , Ines Barroso , Panos Deloukas , Christopher G Mathew , Jenefer M Blackwell , Matthew A Brown , Aiden P Corvin , Mark I McCarthy , Chris C A Spencer , Elvira Bramon , Aiden P Corvin , Michael C O'Donovan , Kari Stefansson , Edward Scolnick , Shaun Purcell , Steven A McCarroll , Pamela Sklar , Christina M Hultman , Patrick F Sullivan |
2013-10-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20164573 |
J. Alzheimers Dis. Nobuto Shibata , Bolati Kuerban , Miwa Komatsu , Tohru Ohnuma , Hajime Baba , Heii Arai |
2010-01-01 |
CALHM3,
CALHM1,
APOE,
CALHM2
|
| 18585350 |
A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. Cell Ute Dreses-Werringloer , Jean-Charles Lambert , Valérie Vingtdeux , Haitian Zhao , Horia Vais , Adam Siebert , Ankit Jain , Jeremy Koppel , Anne Rovelet-Lecrux , Didier Hannequin , Florence Pasquier , Daniela Galimberti , Elio Scarpini , David Mann , Corinne Lendon , Dominique Campion , Philippe Amouyel , Peter Davies , J Kevin Foskett , Fabien Campagne , Philippe Marambaud |
2008-06-27 |
CALHM3,
CALHM1,
APP,
CALHM2
|
| 16751333 |
Cell-based screening and validation of human novel genes associated with cell viability. J Biomol Screen Lan Wang , Xia Gao , Peng Gao , Weiwei Deng , Peng Yu , Jinjing Ma , Jinhai Guo , Xinyu Wang , Hualing Cheng , Chenying Zhang , Chuanfei Yu , Xi Ma , Bingfeng Lv , Yang Lu , Taiping Shi , Dalong Ma |
2006-06-01 |
RNF122
|
| 16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
| 16385451 |
Am J Hum Genet Andrew Grupe , Yonghong Li , Charles Rowland , Petra Nowotny , Anthony L Hinrichs , Scott Smemo , John S K Kauwe , Taylor J Maxwell , Sara Cherny , Lisa Doil , Kristina Tacey , Ryan van Luchene , Amanda Myers , Fabienne Wavrant-De Vrièze , Mona Kaleem , Paul Hollingworth , Luke Jehu , Catherine Foy , Nicola Archer , Gillian Hamilton , Peter Holmans , Chris M Morris , Joseph Catanese , John Sninsky , Thomas J White , John Powell , John Hardy , Michael O'Donovan , Simon Lovestone , Lesley Jones , John C Morris , Leon Thal , Michael Owen , Julie Williams , Alison Goate |
2006-01-01 | - |
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员