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5106 PCK2

5106

PCK2

phosphoenolpyruvate carboxykinase 2, mitochondrial

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphoenolpyruvate carboxykinase 2, mitochondrial

研究结论

Date Results Publications
2020-12-19 13:42:00 Hypoxia increases the rate of renal gluconeogenesis via hypoxia-inducible factor-1-dependent activation of phosphoenolpyruvate carboxykinase expression. 32045650
2020-07-18 12:16:00 The relationship between PEPCK metabolism in the urinary tract and insulin resistance and diabetes is reported. 32036699
2020-07-04 12:10:00 This study unveiled a novel role for PCK2 in integrating autophagy and bone formation, providing a potential target for stem cell-based bone tissue engineering that may lead to improved therapies for metabolic bone diseases. 31574189
2018-09-01 11:48:00 Our study indicates that the T allele of the rs4982856 single-nucleotide polymorphisms in the PCK2 gene may be a risk factor for glucose intolerance after kidney transplantation 29731064
2017-09-16 10:16:00 Downregulation of PCK2 remodels tricarboxylic acid cycle in tumor-repopulating cells of melanoma 28166201

名称对应

Type IDs
Synonymous PEPCK, PEPCK-M, PEPCK2
Gene
UniProtKB-ID: PCKGM_HUMAN, A0A384MTT2_HUMAN
UniprotKB: Q16822, A0A384MTT2
UniParc: UPI00017A821E, UPI000443805B, UPI0000169DF3
EMBL: GQ891518, AK301400, AK316206, BC001454, Y11484, BX248272, CH471078, X92720, KF455834, AL136295
Ensembl: ENSG00000100889, ENSG00000285241
KO: hsa:5106
Nucleutide sequences
EMBL-CDS: CAA63380.1, CAA72272.1, BAG62935.1, BAH14577.1, AAH01454.1, CAD62600.1, ADO22380.1, EAW66115.1
Gene_ORFName: hCG_40169
Ensembl_TRS: ENST00000396973, ENST00000644679, ENST00000561286, ENST00000645217, ENST00000645536, ENST00000645709, ENST00000216780, ENST00000545054
Protein sequencees
Ensembl_PRO: ENSP00000441826, ENSP00000216780, ENSP00000494919, ENSP00000496102, ENSP00000454011, ENSP00000496343, ENSP00000380171, ENSP00000494029
RefSeq: NP_001018083.2, NP_001294983.1, NP_004554.3, XP_006720221.1, NP_001278485.1
Others
UniRef100: UniRef100_Q16822
UniRef90: UniRef90_Q16822
UniRef50: UniRef50_P35558
UniGene: Hs.75812
CCDS: CCDS9609.1, CCDS76660.1, CCDS41928.1

全选

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