| Type | Description |
|---|---|
| Definition | geminin DNA replication inhibitor |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:14:00 | Targeting AXL and to prevent geminin overexpression-induced triple-negative breast cancer metastasis. | 31844158 |
| 2020-03-14 12:23:00 | Inhibitor Geminin and Retinoic Acid Signaling Participate in Complex Interactions Associated With Pluripotency. | 31659113 |
| 2020-02-01 11:51:00 | This study demonstrated that overexpressing UHRF1 was involved in vascular smooth cells proliferation through reducing inhibitory geminin protein levels to promote cell cycle as well as activating PI3K-Akt signaling. | 30710064 |
| 2019-03-16 12:59:00 | Geminin family members are master regulators of centriole amplification and multiciliogenesis. (Review) | 29243212 |
| 2018-01-27 10:51:00 | High Geminin expression is associated with triple negative breast cancers. | 26989079 |
| Type | IDs |
|---|---|
| Synonymous | Gem, MGORS6 |
| Gene |
UniProtKB-ID:
GEMI_HUMAN,
A0A024QZY7_HUMAN
UniprotKB:
O75496,
A0A024QZY7
UniParc:
UPI000012B3BB
EMBL:
BC005185,
CH471087,
AL133264,
AF067855,
AK021685,
BC005389
Ensembl:
ENSG00000112312
KO:
hsa:51053
|
| Nucleutide sequences |
EMBL-CDS:
AAH05389.1,
BAG51040.1,
AAC39787.1,
AAH05185.1,
EAW55466.1,
EAW55465.1
Gene_ORFName:
hCG_37510
Ensembl_TRS:
ENST00000356509,
ENST00000620958,
ENST00000230056
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000477506,
ENSP00000230056,
ENSP00000348902
RefSeq:
NP_056979.1,
XP_005249216.1,
NP_001238919.1,
NP_001238918.1,
NP_001238920.1,
XP_011512953.1
|
| Others |
UniRef100:
UniRef100_O75496
UniRef90:
UniRef90_O75496
UniRef50:
UniRef50_O75496
UniGene:
Hs.234896
CCDS:
CCDS4560.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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