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5105 PCK1

5105

PCK1

phosphoenolpyruvate carboxykinase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition phosphoenolpyruvate carboxykinase 1

研究结论

Date Results Publications
2021-01-16 15:54:00 Hepatocellular carcinoma cell-derived extracellular vesicles encapsulated microRNA-584-5p facilitates angiogenesis through PCK1-mediated nuclear factor E2-related factor 2 signaling pathway. 32522621
2020-12-19 13:42:00 Hypoxia increases the rate of renal gluconeogenesis via hypoxia-inducible factor-1-dependent activation of phosphoenolpyruvate carboxykinase expression. 32045650
2020-08-22 15:31:00 Cytosolic phosphoenolpyruvate carboxykinase is expressed in alpha-cells from human and murine pancreas. 31180589
2020-06-06 12:45:00 the gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis; findings highlight the importance of the protein kinase activity of PCK1 in the activation of SREBPs, lipogenesis and the development of hepatocellular carcinoma 32322062
2020-05-30 11:16:00 These findings implicate DHODH and PCK1 in the colorectal cancer metastatic progression via pyrimidine nucleotide biosynthesis under hypoxia. 31841108

名称对应

Type IDs
Synonymous PCKDC, PEPCK-C, PEPCK1, PEPCKC
Gene
UniProtKB-ID: PCKGC_HUMAN
UniprotKB: P35558
UniParc: UPI000013CB5A, UPI00017A7B8D
EMBL: CH471077, U31519, AL035541, BC023978, AK300072, L05144, L12760, AK290802, AY794987
Ensembl: ENSG00000124253
KO: hsa:5105
Nucleutide sequences
EMBL-CDS: AAA91026.1, AAA02558.1, EAW75514.1, AAH23978.1, BAF83491.1, AAA60084.1, AAV50001.1, BAG61876.1
Ensembl_TRS: ENST00000319441
Protein sequencees
Ensembl_PRO: ENSP00000319814
RefSeq: NP_002582.3, XP_024307656.1
Others
UniRef100: UniRef100_P35558
UniRef90: UniRef90_P35558
UniRef50: UniRef50_P35558
UniGene: Hs.1872
CCDS: CCDS13460.1

全选

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研究热度

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