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51043 ZBTB7B

51043

ZBTB7B

zinc finger and BTB domain containing 7B

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger and BTB domain containing 7B

研究结论

Date Results Publications
2021-02-27 13:45:00 Zbtb7b suppresses aseptic inflammation by regulating m(6)A modification of IL6 mRNA. 32828308
2020-11-21 13:33:00 Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair. 32098917
2019-07-13 11:45:00 In vitro, prolonged activation of naive CD4 T cells in presence of Th1 polarizing cytokines led to the acquisition of perforin-dependent cytotoxic activity. This process was dependent on the Th1 transcription factor Runx3 and was limited by the sustained expression of ThPOK. 29488879
2019-03-30 11:08:00 Authors show that the transcription factor ThPOK binds cooperatively with NF-kappaB to NRCs and mediates their physical proximity with the IFNB1 gene via its ability to oligomerize when bound to DNA. 30017585
2013-08-10 10:36:00 a novel pathway by which TIP60 and ThPOK synergistically suppresses Eomes function and IFNgamma production, which could contribute to the regulation of inflammation. 23609452

名称对应

Type IDs
Synonymous CKROX, THPOK, ZBTB15, ZFP-67, ZFP67, ZNF857B, c-KROX, hcKROX
Gene
UniProtKB-ID: ZBT7B_HUMAN
UniprotKB: O15156
UniParc: UPI0001A5EB6F, UPI0000073A63
EMBL: AL451085, CH471121, AF007833, BC012070, AK304762, CR749303
Ensembl: ENSG00000160685
KO: hsa:51043
Nucleutide sequences
EMBL-CDS: BAG65517.1, AAC51847.1, CAH18158.1, EAW53149.1, EAW53150.1, AAH12070.1, EAW53151.1
Ensembl_TRS: ENST00000417934, ENST00000292176, ENST00000535420, ENST00000368426
Protein sequencees
Ensembl_PRO: ENSP00000438647, ENSP00000357411, ENSP00000406286, ENSP00000292176
RefSeq: XP_006711419.1, NP_001364381.1, XP_006711420.1, NP_001239335.1, XP_006711421.1, XP_006711422.1, NP_001364382.1, NP_001364383.1, XP_006711417.1, NP_001364380.1, NP_001243384.1, XP_011507901.1, XP_016856888.1, XP_011507900.1, NP_001364384.1
Others
UniRef100: UniRef100_O15156
UniRef90: UniRef90_O15156
UniRef50: UniRef50_O15156
UniGene: Hs.729279, Hs.744441
CCDS: CCDS58030.1, CCDS1081.1

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