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51025 PAM16

51025

PAM16

presequence translocase associated motor 16

protein-coding

Homo sapiens

基因描述

Type Description
Definition presequence translocase associated motor 16

研究结论

Date Results Publications
2019-04-20 12:16:00 Findings demonstrate that Magmas is overexpressed in tissue sections from glioma patients and xenografts. In vivo studies showed that a novel Magmas small molecule inhibitor, BT#9, could cross the BBB in mice. In vitro studies revealed that BT#9 significantly decreased cell proliferation, induced apoptosis, and blocked migration and invasion. 30414099
2017-05-07 01:43:00 Both DnaJC15 and DnaJC19 formed two distinct subcomplexes with Magmas at the import channel. 27330077
2015-09-12 11:08:00 A novel essential role of Magmas is a regulatory protein' in the maintenance of cellular redox homeostasis and imparting cytoprotection under oxidative stress. 25165880
2014-11-29 10:08:00 finding of deleterious MAGMAS mutations in an early lethal skeletal dysplasia supports a key role for this mitochondrial protein in the ossification process 24786642
2010-12-05 22:08:00 Observational study of gene-disease association. (HuGE Navigator) 20877624

名称对应

Type IDs
Synonymous CGI-136, MAGMAS, SMDMDM, TIM16, TIMM16
Gene
UniProtKB-ID: TIM16_HUMAN
UniprotKB: Q9Y3D7
UniParc: UPI000012EB2D
EMBL: CR457362, BC005024, AK026514, AF151894, AF349455
Ensembl: ENSG00000282228, ENSG00000217930
KO: hsa:51025
Nucleutide sequences
EMBL-CDS: AAH05024.1, AAL57767.1, CAG33643.1, AAD34131.1, BAB15494.1
Gene_ORFName: CGI-136
Ensembl_TRS: ENST00000634045, ENST00000318059, ENST00000616009, ENST00000576217
Protein sequencees
Ensembl_PRO: ENSP00000315693, ENSP00000487678, ENSP00000461047, ENSP00000484240
RefSeq: NP_057153.8
Others
UniRef100: UniRef100_Q9Y3D7
UniRef90: UniRef90_Q9Y3D7
UniRef50: UniRef50_Q9Y3D7
UniGene: Hs.730693
CCDS: CCDS10512.1

全选

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