| Type | Description |
|---|---|
| Definition | T-box 22 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-27 12:02:00 | Findings indicate the important role of T-box 22 protein (TBX22) in familial cases with X-linked cleft palate. | 29932061 |
| 2016-06-28 10:47:00 | we analysed two TBX22 promoter rs7055763 and rs41307258 single-nucleotide polymorphisms (SNPs) in 173 patients with NSCLP and 176 normal controls of south Indian origin using Kbioscience KASPar chemistry | 25918826 |
| 2015-04-18 10:15:00 | These results suggest that a loss-of-function mutation in the X-linked TBX22 promoter may cause the cleft palate through disruption of TBX22-ETS-1 pathway. | 25373698 |
| 2014-01-18 10:07:00 | TBX22 is the gene underlying Abruzzo-Erickson syndrome. | 22784330 |
| 2011-06-04 10:16:00 | 5 putative missense mutations were identified, 3 located in T-box binding domain (R120Q, R126W, and R151L) that affects DNA binding and/or transcriptional repression. 2 novel C-terminal mutations, P389Q and S400Y, did not affect TBX22 activity. | 21248356 |
| Type | IDs |
|---|---|
| Synonymous | ABERS, CLPA, CPX, TBXX, dJ795G23.1 |
| Gene |
UniProtKB-ID:
TBX22_HUMAN,
B3KUL8_HUMAN
UniprotKB:
Q9Y458,
B3KUL8
UniParc:
UPI000153C47C,
UPI00001377ED,
UPI0000000DDD
EMBL:
AY035371,
AF251684,
AK097514,
BC014194,
CH471104,
AL031000
Ensembl:
ENSG00000122145,
ENSG00000277800
KO:
hsa:50945
|
| Nucleutide sequences |
EMBL-CDS:
AAH14194.2,
EAW98588.1,
AAG23749.1,
AAK63189.1,
BAG53480.1
Ensembl_TRS:
ENST00000373294,
ENST00000619509,
ENST00000373296,
ENST00000628957
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362390,
ENSP00000362393,
ENSP00000479825,
ENSP00000487295
RefSeq:
NP_001103348.1,
NP_001103349.1,
NP_058650.1,
NP_001290404.1
|
| Others |
UniRef100:
UniRef100_B3KUL8,
UniRef100_Q9Y458
UniRef90:
UniRef90_B3KUL8,
UniRef90_Q9Y458
UniRef50:
UniRef50_B3KUL8,
UniRef50_Q9Y458
UniGene:
Hs.374253
CCDS:
CCDS14445.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员