| Type | Description |
|---|---|
| Definition | tumor necrosis factor (ligand) superfamily, member 14 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:52:00 | LIGHT/LTbetaR signaling regulates self-renewal and differentiation of hematopoietic and leukemia stem cells. | 33594067 |
| 2020-11-21 13:20:00 | Increased LIGHT expression and activation of non-canonical NF-kappaB are observed in gastric lesions of MyD88-deficient mice upon Helicobacter felis infection. | 31065023 |
| 2020-07-11 11:50:00 | Light protein deficiency in a high-fat high-cholesterol diet improves hepatic glucose tolerance, and reduces hepatic inflammation and non-alcoholic fatty liver disease; this is accompanied by decreased systemic inflammation and adipose tissue cytokine secretion and by changes in the expression of key genes such as Klf6 and Tlr4 involved in NAFLD | 31388695 |
| 2019-10-26 11:02:00 | LIGHT stimulation increases OPG levels in B, CD8(+) T, and osteoblastic cells, as well as Wnt10b expression in CD8(+) T cells. The high bone mass in Light and T- and B-cell-deficient mice (Rag(-) /Tnfsf14(-) ) supports the cooperative role of the immune system in bone homeostasis. | 29178458 |
| 2019-10-12 10:05:00 | LIGHT signaling through lymphotoxin beta receptor plays a critical role in the progression of experimental colitis | 30524422 |
| Type | IDs |
|---|---|
| Synonymous | HVEM-L, HVEML, LIGHT, LTg, Ly113, Tnlg1d |
| Gene |
UniProtKB-ID:
TNF14_MOUSE,
A0A0U5JAA8_MOUSE
UniprotKB:
Q9QYH9,
A0A0U5JAA8
UniParc:
UPI0000020F00
EMBL:
BC125477,
AF123385,
BC125479,
AF227533,
LN874393,
AB029155
Ensembl:
ENSMUSG00000005824
KO:
mmu:50930
|
| Nucleutide sequences |
EMBL-CDS:
AAF76453.1,
AAI25480.1,
AAF36722.1,
BAA88559.1,
AAI25478.1,
CTQ86158.1
Ensembl_TRS:
ENSMUST00000005976
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005976
RefSeq:
NP_062291.1
|
| Others |
UniRef100:
UniRef100_Q9QYH9
UniRef90:
UniRef90_Q9QYH9
UniRef50:
UniRef50_O43557
UniGene:
Mm.483369
CCDS:
CCDS28928.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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