| Type | Description |
|---|---|
| Definition | growth factor receptor bound protein 14 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:33:00 | Inhibition of Grb14, a negative modulator of insulin signaling, improves glucose homeostasis without causing cardiac dysfunction. | 32099031 |
| 2017-05-13 13:42:00 | Study reveals that Grb14 acts as a new signaling node that regulates lipogenesis and modulates insulin sensitivity in the liver by acting at a crossroad between the insulin receptor and the p62-Nrf2-LXR signaling pathways. | 27215388 |
| 2014-02-22 13:01:00 | The phosphorylation status of the BPS region of Grb14 determines the positive or negative role it will play in insulin receptor signaling. | 24350791 |
| 2011-12-17 11:59:00 | Data show that Grb14 inhibits the activity of PTP1B in retina in a phosphorylation-regulated manner, and that rhodopsin-regulated Src kinase activation in retina leads to the phosphorylation of Grb14. | 21791607 |
| 2011-02-05 10:08:00 | Grb14 is a normal physiological modulator of CNG channel function in vivo. | 20890309 |
| Type | IDs |
|---|---|
| Synonymous | AI505286 |
| Gene |
UniProtKB-ID:
GRB14_MOUSE,
A2ASX2_MOUSE
UniprotKB:
Q9JLM9,
A2ASX2
UniParc:
UPI0000022A3D
EMBL:
AK010903,
BC021820,
AK010849,
AK147041,
AF155647,
BC145913,
BC138581
Ensembl:
ENSMUSG00000026888
KO:
mmu:50915
|
| Nucleutide sequences |
EMBL-CDS:
BAB27221.3,
AAH21820.1,
AAF43996.1,
BAE27629.1,
BAB27256.3,
AAI45914.1,
AAI38582.1
Ensembl_TRS:
ENSMUST00000028252
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028252
RefSeq:
XP_006499946.1,
XP_036018262.1,
XP_036018263.1,
NP_057928.1
|
| Others |
UniRef100:
UniRef100_Q9JLM9
UniRef90:
UniRef90_Q9JLM9
UniRef50:
UniRef50_Q9JLM9
UniGene:
Mm.214554
CCDS:
CCDS16071.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员